Primary study · included by 1 review
No findings of dental defects in children treated with minocycline.
Cascio 2004 · Cascio Antonio, Di Liberto Chiara, D'Angelo Matteo, et al. · Antimicrobial agents and chemotherapy · 2004
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Permanent dental staining Newer-generation tetracycline derivatives (doxycycline, minocycline, tigecycline) vs Children not exposed to tetracycline derivatives · Dental examination at mean age 9.8 to 11.6 years | RD 0.01 [-0.038, 0.057] | 2 studies · 184 participants | GRADE not reported |
Permanent dental staining Newer-generation tetracycline derivatives (doxycycline, minocycline, tigecycline) vs Children not exposed to tetracycline derivatives · Dental examination at mean age 9.8 to 11.6 years | RD 0.007 [-0.015, 0.028] | 3 studies · 455 participants | Low |
Permanent dental staining Newer-generation tetracycline derivatives (doxycycline, minocycline, tigecycline) vs Children not exposed to tetracycline derivatives · Dental examination at mean age 9.8 to 11.6 years | RD 0.005 [-0.017, 0.028] | 2 studies · 332 participants | GRADE not reported |
Permanent dental staining Newer-generation tetracycline derivatives (doxycycline, minocycline, tigecycline) vs Children not exposed to tetracycline derivatives · Dental examination at mean age 9.8 to 11.6 years | RD 0.008 [-0.015, 0.031] | 2 studies · 394 participants | GRADE not reported |
1 including review in total.