Primary study · included by 1 review

Randomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps.

Roffe 2002 · Roffe Christine, Sills Sheila, Crome Peter, et al. · Medical science monitor : international medical journal of experimental and clinical research · 2002

Included by

The Role of Electrolytes in Muscle Pain Syndromes: A Systematic Review and Meta-Analysis With Implications for Temporomandibular Disorder.

Non-Cochrane · intervention · 2026 · cited as Roffe 2002 · Reference list; Table 2

Outcome this study informs	Pooled effect	Evidence	Certainty
Cramp frequency (cramps per week) Oral magnesium supplementation vs Placebo · Treatment period (4 weeks to 60 days)	MD -0.42 [-1.15, 0.31]	4 studies · 396 participants	GRADE not reported

1 including review in total.