Primary study · included by 1 review

Riad 2020

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Outcome this study informsPooled effectEvidenceCertainty
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -2.18 [-3.92, -0.45]5 studiesGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.43 [-14.11, 11.25]2 studiesGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.68 [-2.71, -0.67]8 studies · 395 participantsVery low
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.85 [-3.81, 0.11]5 studies · 206 participantsGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.63 [-3.65, 0.4]3 studies · 158 participantsGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.8 [-7.49, 3.89]3 studiesGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -2.13 [-4.61, 0.35]2 studiesGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.8 [-3.14, -0.47]6 studiesGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.75 [-2.99, -0.53]7 studiesGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.8 [-3.14, -0.47]6 studiesGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -1.43 [-14.11, 11.25]2 studiesGRADE not reported
White spot lesion quantification (score, lesion size, fluorescence loss, microhardness, color change, mineral content)
Self-assembling peptide P11-4 (alone or with fluoride or ACP) vs Fluoride varnish, ACP varnish or no treatment · 6 weeks to 6 months
SMD -0.68 [-2.21, 0.85]2 studiesGRADE not reported

1 including review in total.