Primary study · included by 1 review
Renouf 2024
ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Osteoradionecrosis of the jaws (ORNJ) N1 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.19 [0.74, 1.92] | 3 studies · 1601 participants | Moderate |
Osteoradionecrosis of the jaws (ORNJ) N3 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.02 [0.41, 2.55] | 3 studies · 2006 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) Oral cavity cancer (tumor site) (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 4.81 [1.56, 14.9] | 4 studies · 6872 participants | GRADE not reported |
Development of osteoradionecrosis of the jaws (ORNJ) Oropharyngeal tumor vs Non-oropharyngeal tumor | OR 2.61 [0.32, 21.52] | 3 studies · 1810 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) N0 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.01 [0.66, 1.54] | 3 studies · 1601 participants | Low |
Osteoradionecrosis of the jaws (ORNJ) Oropharyngeal tumor (tumor site) (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 2.34 [1.63, 3.34] | 3 studies · 1810 participants | Moderate |
Osteoradionecrosis of the jaws (ORNJ) N0 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.73 [0.73, 4.08] | 3 studies · 2006 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) N2 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | RR 0.9 [0.71, 1.15] | 3 studies · 2006 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) N3 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 0.57 [0.25, 1.34] | 3 studies · 1601 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) Oropharyngeal tumor (tumor site) (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 2.61 [0.32, 21.52] | 3 studies · 1810 participants | GRADE not reported |
Development of osteoradionecrosis of the jaws (ORNJ) Diabetes mellitus vs No diabetes mellitus | OR 1.01 [0.86, 1.19] | 7 studies · 23068 participants | Moderate |
Osteoradionecrosis of the jaws (ORNJ) T4 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.75 [0.69, 4.45] | 4 studies · 4049 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) T4 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.98 [1.38, 2.84] | 4 studies · 2825 participants | Low |
Osteoradionecrosis of the jaws (ORNJ) N1 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.2 [0.74, 1.96] | 3 studies · 1601 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) T3 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.3 [0.91, 1.86] | 4 studies · 2825 participants | Low |
Osteoradionecrosis of the jaws (ORNJ) Diabetes mellitus (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.01 [0.86, 1.19] | 7 studies · 23068 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) Tobacco use (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 2.18 [0.73, 6.49] | 7 studies · 3422 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) N1 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.51 [1.02, 2.26] | 3 studies · 3031 participants | GRADE not reported |
Development of osteoradionecrosis of the jaws (ORNJ) T1 tumor stage vs Other T stages | OR 2.44 [0.12, 48.28] | 4 studies · 2825 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) Tobacco use (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 2.56 [1.96, 3.34] | 7 studies · 3422 participants | Moderate |
Osteoradionecrosis of the jaws (ORNJ) Tobacco use (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 3.44 [1.22, 9.73] | 7 studies · 3930 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) N3 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 0.6 [0.31, 1.19] | 3 studies · 1601 participants | Moderate |
Osteoradionecrosis of the jaws (ORNJ) T2 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.78 [1.32, 2.41] | 4 studies · 2825 participants | Low |
Development of osteoradionecrosis of the jaws (ORNJ) Oral cancer (oral cavity tumor site) vs No oral cancer (other tumor sites) | OR 4.81 [1.56, 14.9] | 4 studies · 6872 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) N2 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | RR 1.03 [0.82, 1.3] | 3 studies · 1601 participants | GRADE not reported |
Development of osteoradionecrosis of the jaws (ORNJ) Diabetes mellitus vs No diabetes mellitus | OR 1.01 [0.86, 1.19] | 7 studies · 23068 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) N2 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | RR 1.01 [0.87, 1.17] | 3 studies · 1601 participants | Moderate |
Osteoradionecrosis of the jaws (ORNJ) Good oral hygiene (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 0.39 [0.21, 0.76] | 2 studies · 337 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) Oral cavity cancer (tumor site) (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 4 [2.9, 5.51] | 4 studies · 6872 participants | Moderate |
Osteoradionecrosis of the jaws (ORNJ) Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.42 [0.47, 4.29] | 7 studies · 24677 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 0.72 [0.19, 2.72] | 7 studies · 26135 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) T1 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 2.44 [0.12, 48.28] | 4 studies · 2825 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) T2 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 2.9 [0.71, 11.81] | 4 studies · 2996 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) T1 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.01 [0.62, 1.65] | 4 studies · 2825 participants | Low |
Development of osteoradionecrosis of the jaws (ORNJ) Good oral hygiene vs Poor or fair oral hygiene | OR 0.4 [0.21, 0.76] | 2 studies · 337 participants | Moderate |
Osteoradionecrosis of the jaws (ORNJ) T2 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 2.05 [0.42, 9.98] | 4 studies · 2825 participants | GRADE not reported |
Development of osteoradionecrosis of the jaws (ORNJ) T3 tumor stage vs Other T stages | OR 1.98 [0.44, 8.81] | 4 studies · 2825 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 0.84 [0.74, 0.94] | 7 studies · 24677 participants | Low |
Osteoradionecrosis of the jaws (ORNJ) T4 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 2.44 [1.08, 5.51] | 4 studies · 2825 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) N0 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 0.97 [0.45, 2.09] | 3 studies · 1601 participants | GRADE not reported |
Osteoradionecrosis of the jaws (ORNJ) T3 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified | OR 1.98 [0.44, 8.81] | 4 studies · 2825 participants | GRADE not reported |
1 including review in total.