Primary study · included by 1 review

Nawal 2024

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Inflammatory Biomarkers in Irreversible Pulpitis and Pulp Necrosis: A Systematic Review and Meta-Analysis.
Non-Cochrane · aetiology · 2026 · cited as Nawal 2024 · Table 1; Fig 2, Fig 3 and Supplementary Figures
Outcome this study informsPooled effectEvidenceCertainty
TNF-α level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -2.08 [-3.46, -0.7]5 studies · 194 participantsLow
IL-8 level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -1.86 [-2.42, -1.3]6 studies · 243 participantsLow
IL-8 level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -1.9 [-4.13, 0.34]2 studies · 65 participantsGRADE not reported
IL-8 level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -1.96 [-2.89, -1.02]4 studies · 142 participantsGRADE not reported
IL-8 level
Symptomatic irreversible pulpitis (SIP) vs Healthy pulp · Single time point (biomarker level at diagnosis/sampling)
SMD -1.95 [-2.64, -1.26]5 studies · 203 participantsGRADE not reported
TNF-α level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -2.6 [-3.95, -1.25]4 studies · 159 participantsGRADE not reported
TNF-α level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -3.71 [-7.07, -0.35]2 studies · 82 participantsGRADE not reported

1 including review in total.