Primary study · included by 1 review

Liao 2021

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Identifying risk factors for osteoradionecrosis of the jaws: a systematic review and meta-analysis.
Non-Cochrane · aetiology · 2026 · cited as Liao 2021 · Fig. 2-5 forest plot; Table 1
Outcome this study informsPooled effectEvidenceCertainty
Development of osteoradionecrosis of the jaws (ORNJ)
Diabetes mellitus vs No diabetes mellitus
OR 1.01 [0.86, 1.19]7 studies · 23068 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
Tooth extraction after radiotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 8.38 [7.2, 9.77]3 studies · 17508 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
Diabetes mellitus (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.01 [0.86, 1.19]7 studies · 23068 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Tooth extraction before radiotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.15 [1.01, 1.31]4 studies · 17674 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
Tooth extraction after radiotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 8.5 [7.34, 9.85]3 studies · 18315 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Tooth extraction before radiotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.98 [0.67, 1.45]4 studies · 17674 participantsGRADE not reported
Development of osteoradionecrosis of the jaws (ORNJ)
Diabetes mellitus vs No diabetes mellitus
OR 1.01 [0.86, 1.19]7 studies · 23068 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Tooth extraction after radiotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 8.32 [7.15, 9.7]3 studies · 17508 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.42 [0.47, 4.29]7 studies · 24677 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.72 [0.19, 2.72]7 studies · 26135 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.84 [0.74, 0.94]7 studies · 24677 participantsLow
Osteoradionecrosis of the jaws (ORNJ)
Tooth extraction before radiotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.09 [0.75, 1.58]4 studies · 17840 participantsGRADE not reported

1 including review in total.