Primary study · included by 1 review

Kritikou 2021

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Inflammatory Biomarkers in Irreversible Pulpitis and Pulp Necrosis: A Systematic Review and Meta-Analysis.
Non-Cochrane · aetiology · 2026 · cited as Kritikou 2021 · Table 1; Fig 2, Fig 3 and Supplementary Figures
Outcome this study informsPooled effectEvidenceCertainty
Catalase level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -1.41 [-2.35, -0.46]3 studies · 113 participantsLow
TNF-α level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -2.08 [-3.46, -0.7]5 studies · 194 participantsLow
MMP-9 level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -2.0 [-3.48, -0.51]2 studies · 82 participantsGRADE not reported
IL-2 level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -1.61 [-3.14, -0.08]4 studies · 169 participantsLow
IL-2 level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -1.54 [-3.62, 0.55]3 studies · 122 participantsGRADE not reported
Catalase level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -1.84 [-2.42, -1.26]2 studies · 71 participantsGRADE not reported
MMP-9 level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -1.27 [-2.85, 0.31]3 studies · 124 participantsLow
TNF-α level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -2.6 [-3.95, -1.25]4 studies · 159 participantsGRADE not reported
TNF-α level in dental pulp
Symptomatic irreversible pulpitis (exposure) vs Healthy pulp
SMD -3.71 [-7.07, -0.35]2 studies · 82 participantsGRADE not reported

1 including review in total.