Primary study · included by 1 review

Kaur 2023

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Nonsteroidal anti-inflammatory drug (NSAID) premedication for pain-free inferior alveolar nerve block: a systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Kaur 2023 · Ref 46; Table 1

Outcome this study informs	Pooled effect	Evidence	Certainty
Pain-free initial IANB success without supplemental anesthesia Any oral NSAID before IANB vs Oral placebo before IANB · Intraoperative assessment, procedural steps vary by trial	RR 2.27 [1.81, 2.85]	6 studies · 510 participants	GRADE not reported
Pain-free IANB success (no intraoperative pain at any recorded step after initial IANB and no supplemental anesthesia) Oral NSAID premedication (any agent) + IANB vs Oral placebo + IANB · Intraoperative, after initial IANB (access and/or instrumentation or pulp extirpation)	RR 2.31 [1.89, 2.83]	10 studies	GRADE not reported
Pain-free initial IANB success without supplemental anesthesia Any oral NSAID before IANB vs Oral placebo before IANB · Intraoperative assessment, procedural steps vary by trial	RR 2.06 [1.48, 2.86]	11 studies · 737 participants	Low
Pain-free initial IANB success without supplemental anesthesia Any oral NSAID before IANB vs Oral placebo before IANB · Intraoperative assessment, procedural steps vary by trial	RR 2.28 [1.84, 2.82]	7 studies · 576 participants	GRADE not reported
Pain-free IANB success (no intraoperative pain at any recorded step after initial IANB and no supplemental anesthesia) Oral NSAID premedication (any agent) + IANB vs Oral placebo + IANB · Intraoperative, after initial IANB (access and/or instrumentation or pulp extirpation)	RR 2.01 [1.44, 2.81]	10 studies	GRADE not reported

1 including review in total.