Primary study · included by 1 review

Caparrotti 2017

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Identifying risk factors for osteoradionecrosis of the jaws: a systematic review and meta-analysis.
Non-Cochrane · aetiology · 2026 · cited as Caparrotti 2017 · Fig. 2-5 forest plot; Table 1
Outcome this study informsPooled effectEvidenceCertainty
Development of osteoradionecrosis of the jaws (ORNJ)
Tumor located at the base of the tongue vs Tumor not at the base of the tongue
OR 0.75 [0.48, 1.18]2 studies · 1430 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
N1 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.19 [0.74, 1.92]3 studies · 1601 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
Tonsillar region tumor (tumor site) (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.32 [0.87, 2.01]2 studies · 1430 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N3 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.02 [0.41, 2.55]3 studies · 2006 participantsGRADE not reported
Development of osteoradionecrosis of the jaws (ORNJ)
N2b nodal stage vs Other N stages
RR 0.89 [0.65, 1.2]2 studies · 1430 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
N0 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.01 [0.66, 1.54]3 studies · 1601 participantsLow
Osteoradionecrosis of the jaws (ORNJ)
N0 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.73 [0.73, 4.08]3 studies · 2006 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N2 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
RR 0.9 [0.71, 1.15]3 studies · 2006 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N3 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.57 [0.25, 1.34]3 studies · 1601 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Neck dissection (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.47 [0.88, 2.45]2 studies · 1430 participantsLow
Osteoradionecrosis of the jaws (ORNJ)
N2b nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
RR 0.89 [0.65, 1.2]2 studies · 1430 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N2c nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.15 [0.73, 1.82]2 studies · 1430 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
T4 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.75 [0.69, 4.45]4 studies · 4049 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
T4 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.98 [1.38, 2.84]4 studies · 2825 participantsLow
Osteoradionecrosis of the jaws (ORNJ)
N1 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.2 [0.74, 1.96]3 studies · 1601 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N2a nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.72 [0.17, 3.06]2 studies · 1430 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
T3 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.3 [0.91, 1.86]4 studies · 2825 participantsLow
Osteoradionecrosis of the jaws (ORNJ)
Neck dissection (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.39 [0.58, 3.33]2 studies · 1430 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Tobacco use (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 2.18 [0.73, 6.49]7 studies · 3422 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N1 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.51 [1.02, 2.26]3 studies · 3031 participantsGRADE not reported
Development of osteoradionecrosis of the jaws (ORNJ)
T1 tumor stage vs Other T stages
OR 2.44 [0.12, 48.28]4 studies · 2825 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Tobacco use (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 2.56 [1.96, 3.34]7 studies · 3422 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
Tobacco use (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 3.44 [1.22, 9.73]7 studies · 3930 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N3 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.6 [0.31, 1.19]3 studies · 1601 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
T2 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.78 [1.32, 2.41]4 studies · 2825 participantsLow
Osteoradionecrosis of the jaws (ORNJ)
N2 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
RR 1.03 [0.82, 1.3]3 studies · 1601 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Base of tongue tumor (tumor site) (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.75 [0.48, 1.18]2 studies · 1430 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N2 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
RR 1.01 [0.87, 1.17]3 studies · 1601 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.42 [0.47, 4.29]7 studies · 24677 participantsGRADE not reported
Development of osteoradionecrosis of the jaws (ORNJ)
Tumor located in the tonsillar region vs Tumor not in the tonsillar region
OR 1.32 [0.87, 2.01]2 studies · 1430 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.72 [0.19, 2.72]7 studies · 26135 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
T1 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 2.44 [0.12, 48.28]4 studies · 2825 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
T2 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 2.9 [0.71, 11.81]4 studies · 2996 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
T1 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.01 [0.62, 1.65]4 studies · 2825 participantsLow
Osteoradionecrosis of the jaws (ORNJ)
T2 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 2.05 [0.42, 9.98]4 studies · 2825 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N2a nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.58 [0.24, 1.41]2 studies · 1430 participantsModerate
Development of osteoradionecrosis of the jaws (ORNJ)
T3 tumor stage vs Other T stages
OR 1.98 [0.44, 8.81]4 studies · 2825 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
Chemotherapy (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.84 [0.74, 0.94]7 studies · 24677 participantsLow
Development of osteoradionecrosis of the jaws (ORNJ)
N2c nodal stage vs Other N stages
OR 1.15 [0.73, 1.82]2 studies · 1430 participantsModerate
Osteoradionecrosis of the jaws (ORNJ)
T4 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 2.44 [1.08, 5.51]4 studies · 2825 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
N0 nodal stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 0.97 [0.45, 2.09]3 studies · 1601 participantsGRADE not reported
Osteoradionecrosis of the jaws (ORNJ)
T3 tumor stage (frequency among patients who developed ORNJ) vs Same factor among irradiated patients who did not develop ORNJ · Not specified
OR 1.98 [0.44, 8.81]4 studies · 2825 participantsGRADE not reported

1 including review in total.