Primary study · included by 2 reviews

Brosco 2009

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Impact of Endodontic Treatment of Teeth With Apical Periodontitis on Levels of Inflammatory Biomarkers Associated With Cardiovascular Risk: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as Brosco 2009 · Table 1; References

The review does not say which of its outcomes this study informs.

Does endodontic treatment modify serum inflammatory markers of cardiovascular risk in individuals with asymptomatic apical periodontitis? a systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Brosco 2009 · Table 1; Figs. 2-4; reference list

Outcome this study informs	Pooled effect	Evidence	Certainty
Serum C-reactive protein (CRP) Endodontic treatment (non-surgical treatment or retreatment, with or without surgery) vs Internal control group (healthy individuals; own-control analysis) · Baseline (before treatment)	MD 2.86 [1.30, 4.43]	4 studies	GRADE not reported
Serum C-reactive protein (CRP) Endodontic treatment (non-surgical treatment or retreatment, with or without surgery) vs Internal control group (healthy individuals; own-control analysis) · Post-treatment (follow-up 7 days to 12 months)	MD 0.05 [-0.01, 0.10]	7 studies	GRADE not reported
Serum C-reactive protein (CRP) Endodontic treatment (non-surgical treatment or retreatment, with or without surgery) vs Internal control group (healthy individuals; own-control analysis) · Baseline (before treatment)	MD 0.05 [0.01, 0.10]	3 studies	GRADE not reported
Serum C-reactive protein (CRP) Endodontic treatment (non-surgical treatment or retreatment, with or without surgery) vs Internal control group (healthy individuals; own-control analysis) · Baseline (before treatment)	MD 0.24 [0.07, 0.40]	7 studies	GRADE not reported
Serum C-reactive protein (CRP) Endodontic treatment (non-surgical treatment or retreatment, with or without surgery) vs Internal control group (healthy individuals; own-control analysis) · Post-treatment (follow-up 7 days to 12 months)	MD 0.04 [0.03, 0.04]	3 studies	GRADE not reported
Serum C-reactive protein (CRP) Endodontic treatment (non-surgical treatment or retreatment, with or without surgery) vs Internal control group (healthy individuals; own-control analysis) · Post-treatment (follow-up 7 days to 12 months)	MD 1.24 [0.05, 2.44]	4 studies	GRADE not reported

2 including reviews in total.