Primary study · included by 1 review

Adigun 2022

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Efficacy comparison of articaine versus lidocaine in dental anesthesia: a meta-analysis of randomized controlled trials.

Non-Cochrane · intervention · 2026 · cited as Adigun 2022 · Reference 11; Results (studies cited per outcome); Table 1

Outcome this study informs	Pooled effect	Evidence	Certainty
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 8.2 [-4.76, 21.16]	3 studies	GRADE not reported
Anesthetic onset time (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -1.81 [-2.85, -0.78]	5 studies	GRADE not reported
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 27.34 [9.52, 45.16]	4 studies	GRADE not reported
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 27.34 [9.52, 45.16]	4 studies	GRADE not reported
Anesthetic duration 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 18.68 [3.05, 34.30]	7 studies · 476 participants	Moderate
Anesthetic onset time (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -0.57 [-0.99, -0.16]	2 studies	GRADE not reported
Anesthetic onset time 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -1.34 [-2.21, -0.47]	7 studies · 705 participants	Low
Anesthetic duration (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD 10.02 [-3.71, 23.74]	2 studies	GRADE not reported
Anesthetic onset time (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -2.2 [-3.36, -1.03]	3 studies	GRADE not reported
Anesthetic onset time (min) 4% articaine with epinephrine, infiltration anesthesia vs 2% lidocaine with epinephrine, infiltration anesthesia	MD -0.59 [-2.12, 0.95]	4 studies	GRADE not reported

1 including review in total.