Primary study · included by 1 review

Comparative Evaluation of Topical Application of 5-Fluorouracil and Modified Carnoy’s Solution in Management of Odontogenic Keratocyst

Mishra 2023 · Mishra Nilesh, Dadhich Anuj, Vande Aadite V., et al. · Annals of Dental Specialty · 2023

Included by

Exploring the use and efficacy of 5-fluorouracil in the management of odontogenic keratocysts: a systematic review and meta-analysis.
Non-Cochrane · intervention · 2025 · cited as Mishra 2023 · Tables 1 and 2; References
Outcome this study informsPooled effectEvidenceCertainty
Recurrence
5-FU (5% topical) after enucleation and peripheral ostectomy vs Modified Carnoy's solution (MCS) after enucleation and peripheral ostectomy · Follow-up 12 to 108 months across studies
RD -0.199 [-0.283, -0.114]5 studies · 181 participantsModerate
Postoperative paresthesia (any)
5-FU (5% topical) after enucleation and peripheral ostectomy vs Modified Carnoy's solution (MCS) after enucleation and peripheral ostectomy · Follow-up 12 to 108 months across studies
RD -0.158 [-0.281, -0.035]5 studies · 181 participantsModerate
Permanent paresthesia
5-FU (5% topical) after enucleation and peripheral ostectomy vs Modified Carnoy's solution (MCS) after enucleation and peripheral ostectomy · Follow-up 12 to 108 months across studies
RD -0.061 [-0.14, 0.018]5 studies · 181 participantsGRADE not reported

1 including review in total.