evidencegaps
Primary study · included by 1 review

EFFECTS OF THREE ORAL ANALGESICS ON POSTOPERATIVE PAIN FOLLOWING ROOT CANAL PREPARATION: A CONTROLLED CLINICAL TRIAL

Islam 2021 · Islam Shahid, Ali Muhammad, Shaikh Abubakar, et al. · Pakistan Armed Forces Medical Journal · 2021

Included by

Efficacy and safety of single-dose oral postoperative medications in reducing pain after endodontic treatment: a systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Islam 2018 · Table 2; Study characteristics
Outcome this study informsPooled effectEvidenceCertainty
Postoperative pain (VAS) at 6-8 h
Single-dose oral Naproxen after root canal treatment vs Placebo · 6-8 h after treatment
MD -2.62 [-3.97, -1.27]2 studiesModerate
Postoperative pain (VAS) at 6-8 h
Single-dose oral Tramadol after root canal treatment vs Placebo · 6-8 h after treatment
MD -1.22 [-2.61, 0.17]2 studiesLow
Postoperative pain (VAS) at 6-8 h
Single-dose oral Ibuprofen after root canal treatment vs Placebo · 6-8 h after treatment
MD -1.32 [-2.46, -0.17]3 studiesModerate
Postoperative pain (VAS) at 6-8 h
Any single-dose oral analgesic after root canal treatment (all drugs pooled) vs Placebo · 6-8 h after treatment
MD -2.032 [-2.687, -1.376]5 studiesGRADE not reported

1 including review in total.