Primary study · included by 1 review

Is Silver Diamine Fluoride Effective in Arresting Enamel Caries? A Randomized Clinical Trial

Phonghanyudh 2022 · Phonghanyudh Araya, Duangthip Duangporn, Mabangkhru Sirinan, et al. · International Journal of Environmental Research and Public Health · 2022

Included by

Comparative Efficacy of Silver Diamine Fluoride and Sodium Fluoride in Managing Early Childhood Caries: An Updated Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2026 · cited as Phonghanyudh 2022 · Table 2; References 27-35; Figures 2 and 4

Outcome this study informs	Pooled effect	Evidence	Certainty
Odds of developing decayed, missing and filled surfaces (DMFS) 38% silver diamine fluoride (SDF), topical vs 5% sodium fluoride (NaF), topical (mostly varnish) · 6 to 18 months (mostly 12 months)	OR 1.07 [0.70, 1.64]	9 studies · 3266 participants	Low
Odds of developing decayed, missing and filled surfaces (DMFS) 38% silver diamine fluoride (SDF), topical vs 5% sodium fluoride (NaF), topical (mostly varnish) · 6 to 18 months (mostly 12 months)	OR 1.18 [0.59, 2.38]	2 studies	GRADE not reported
Odds of developing decayed, missing and filled surfaces (DMFS) 38% silver diamine fluoride (SDF), topical vs 5% sodium fluoride (NaF), topical (mostly varnish) · 6 to 18 months (mostly 12 months)	OR 0.91 [0.48, 1.76]	3 studies	GRADE not reported
Odds of caries lesion arrest 38% silver diamine fluoride (SDF), topical vs 5% sodium fluoride (NaF), topical	OR 1.41 [1.03, 1.94]	9 studies · 3266 participants	Moderate
Odds of caries lesion arrest 38% silver diamine fluoride (SDF), topical vs 5% sodium fluoride (NaF), topical (mostly varnish) · 6 to 18 months (mostly 12 months)	OR 1.25 [0.88, 1.77]	4 studies	GRADE not reported
Odds of developing decayed, missing and filled surfaces (DMFS) 38% silver diamine fluoride (SDF), topical vs 5% sodium fluoride (NaF), topical (mostly varnish) · 6 to 18 months (mostly 12 months)	OR 1.07 [0.70, 1.64]	9 studies · 3266 participants	GRADE not reported
Odds of caries lesion arrest 38% silver diamine fluoride (SDF), topical vs 5% sodium fluoride (NaF), topical (mostly varnish) · 6 to 18 months (mostly 12 months)	OR 1.71 [0.96, 3.05]	3 studies	GRADE not reported

1 including review in total.