Primary study · included by 1 review
Cocco et al. 2019
Trial PICO
Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.
Results
Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.
Included by
Clinical Effects of Sugar Substitutes on Cariogenic Bacteria: A Systematic Review and Meta-Analysis.
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Change in Mutans streptococci (MS) and Lactobacilli in saliva Stevia (high-intensity/non-nutritive sweetener) in a daily snack vs Baseline (within-group change); white sugar snack is a parallel arm with no between-group effect size reported · 42 days | Cocco 2019 (the only high-intensity sweetener trial): the stevia snack showed a significant decrease in MS (P < .01) and in lactobacilli (P = .03) versus baseline, whereas the white-sugar snack showed no significant… | 1 study · 271 participants | Ungraded |
1 including review in total.