Primary study · included by 1 review
Results of a third Gamma Knife radiosurgery for trigeminal neuralgia
Helis 2021 · Helis Corbin A., Hughes Ryan T., Munley Michael T., et al. · Journal of Neurosurgery · 2021
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient -0.0057 | 7 studies | GRADE not reported |
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient -0.0004 | 8 studies | GRADE not reported |
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient 0.0022 | 8 studies | GRADE not reported |
Facial hypoesthesia after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS | Proportion (%) 39.04 [26.65, 51.42] | 12 studies · 564 participants | GRADE not reported |
BNI pain score I-III (favorable pain outcome) after latest treatment Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After latest (repeat) treatment | Proportion (%) 76.68 [69.70, 82.46] | 13 studies · 606 participants | GRADE not reported |
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS | Proportion (%) 29.07 [22.68, 35.46] | 14 studies · 1404 participants | GRADE not reported |
BNI pain score I-III (favorable pain outcome) at latest follow-up Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · Latest available follow-up (median follow-up 14-74 months across studies) | Proportion (%) 61.94 [35.59, 82.74] | 8 studies · 350 participants | GRADE not reported |
Corneal dryness after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS | Proportion (%) 10.99 [3.42, 21.54] | 3 studies · 199 participants | GRADE not reported |
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS | Proportion (%) 68.44 [58.44, 78.44] | 12 studies · 1078 participants | GRADE not reported |
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient -0.0109 | 9 studies | GRADE not reported |
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient -0.0086 | 6 studies | GRADE not reported |
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient 0.0047 | 8 studies | GRADE not reported |
BNI pain score I-III (favorable pain outcome) after prior treatment Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · Before repeat GKRS (after prior treatment) | Proportion (%) 70.57 [25.81, 94.30] | 10 studies · 481 participants | GRADE not reported |
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient -0.0000 | 10 studies | GRADE not reported |
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient 0.0035 | 10 studies | GRADE not reported |
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient 0.0012 | 6 studies | GRADE not reported |
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) | Meta-regression coefficient -0.0011 | 10 studies | GRADE not reported |
1 including review in total.