Primary study · included by 1 review

Retreatment of trigeminal neuralgia with Gamma Knife radiosurgery: is there an appropriate cumulative dose?

Dvorak 2009 · Dvorak Tomas, Finn Arkadiy, Price Lori Lyn, et al. · Journal of Neurosurgery · 2009

Included by

Repeat gamma knife radiosurgery for recurrent trigeminal neuralgia: a systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Dvorak 2009 · Table 1; reference list
Outcome this study informsPooled effectEvidenceCertainty
Pain recurrence after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient -0.00577 studiesGRADE not reported
Dysgeusia after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS
Proportion (%) 11.31 [3.68, 21.74]2 studies · 53 participantsGRADE not reported
Pain recurrence after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient -0.00048 studiesGRADE not reported
Pain relief after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient 0.00228 studiesGRADE not reported
Facial hypoesthesia after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS
Proportion (%) 39.04 [26.65, 51.42]12 studies · 564 participantsGRADE not reported
BNI pain score I-III (favorable pain outcome) after latest treatment
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After latest (repeat) treatment
Proportion (%) 76.68 [69.70, 82.46]13 studies · 606 participantsGRADE not reported
Pain recurrence after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS
Proportion (%) 29.07 [22.68, 35.46]14 studies · 1404 participantsGRADE not reported
Dysesthesia after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS
Proportion (%) 7.45 [2.59, 14.11]3 studies · 112 participantsGRADE not reported
Pain relief after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS
Proportion (%) 68.44 [58.44, 78.44]12 studies · 1078 participantsGRADE not reported
Pain recurrence after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient -0.01099 studiesGRADE not reported
Masticatory deficit after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS
Proportion (%) 2.93 [0.00, 9.04]2 studies · 67 participantsGRADE not reported
Pain relief after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient -0.00866 studiesGRADE not reported
Pain relief after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient 0.00478 studiesGRADE not reported
Pain recurrence after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient -0.000010 studiesGRADE not reported
Pain recurrence after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient 0.003510 studiesGRADE not reported
Paresthesia after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS
Proportion (%) 11.81 [5.64, 19.57]3 studies · 92 participantsGRADE not reported
Pain relief after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient 0.00126 studiesGRADE not reported
Pain relief after repeat GKRS
Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)
Meta-regression coefficient -0.001110 studiesGRADE not reported

1 including review in total.