Primary study · included by 1 review

The Effectiveness Of Amine Fluoride Mouthwash In Preventing White Spot Lesions During Fixed Orthodontic Therapy: A Randomized Control Trial

Ravikiran 2021 · MDS Sharanya Sabrish · International Journal of Dentistry and Oral Science · 2021

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Fluoride mouthrinses for prevention of initial caries in orthodontic patients - a systematic review and meta-analysis.
Non-Cochrane · intervention · 2025 · cited as Ravikiran 2021 · Table 1A; Table 1B; Reference [16] (amine fluoride; reported mean lesion area, not pooled)
Outcome this study informsPooled effectEvidenceCertainty
Incidence of initial caries around brackets, aesthetic-zone teeth only
Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Control: fluoride toothpaste alone, placebo mouthrinse + toothpaste, or non-fluoride (chlorhexidine) mouthrinse + toothpaste · At debonding (Gorelick index)
In two studies, a significant reduction of the incidence of initial caries around orthodontic brackets was reported in the FMR group when only teeth in the 'aesthetic zone' (central and lateral incisors, canines) were…2 studiesUngraded
Incidence of initial enamel caries / white spot lesions adjacent to bracket base (subject level, dichotomized)
Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Control: fluoride toothpaste alone, placebo mouthrinse + toothpaste, or non-fluoride (chlorhexidine) mouthrinse + toothpaste · End of intervention (6-26 months) to within 6 weeks after debonding
RD -0.07 [-0.14, -0.01]5 studies · 491 participantsUngraded

1 including review in total.