Primary study · included by 1 review
Pyridinium Cross-Links in Bone of Patients with Osteogenesis Imperfecta: Evidence of a Normal Intrafibrillar Collagen Packing
Bank 2000 · Bank Ruud A., Tekoppele Johan M., Janus Guus J. M., et al. · Journal of Bone and Mineral Research · 2000
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Hydroxyproline (HYP) percentage in collagen-I OI collagen-I (patient-derived bone, fibroblast or dentine samples) vs Control (healthy) collagen-I | Printed in Figure 3A as 0.01 [ 0.03, 0.01] (signs not legible); I2 6.0%, tau2 0.00; test for subgroup difference QM 3.37, df 1 | 3 studies · 62 participants | GRADE not reported |
Hydroxyproline (HYP) percentage in collagen-I OI collagen-I (patient-derived bone, fibroblast or dentine samples) vs Control (healthy) collagen-I | Normalized mean difference 0.01 [-0.01, 0.03] | 14 studies · 79 participants | GRADE not reported |
Hydroxyproline (HYP) percentage in collagen-I OI collagen-I (patient-derived bone, fibroblast or dentine samples) vs Control (healthy) collagen-I | Normalized mean difference 0.00 [-0.02, 0.02] | 17 studies · 141 participants | GRADE not reported |
1 including review in total.