Primary study · included by 1 review

Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial

Sahebnasagh 2023 · Sahebnasagh Marzieh, Aksi Vahideh, Eslami Fatemeh, et al. · European Journal of Medical Research · 2023

Included by

Efficacy of topical application of zinc compounds for oral mucosal diseases: A systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Sahebnasagh 2023 · Figure 4; reference list
Outcome this study informsPooled effectEvidenceCertainty
Oral mucositis severity
Topical zinc therapy (zinc sulfate, zinc oxide or zinc chloride mouthwash, paste, spray or gel) vs Control treatments (placebo, chlorhexidine, sodium bicarbonate, polyherbal, standard care) · 3 weeks after treatment initiation
MD -0.41 [-0.79, -0.03]4 studies · 271 participantsGRADE not reported
Oral mucositis severity
Topical zinc therapy (zinc sulfate, zinc oxide or zinc chloride mouthwash, paste, spray or gel) vs Control treatments (placebo, chlorhexidine, sodium bicarbonate, polyherbal, standard care) · 2 weeks after treatment initiation
MD -0.46 [-0.63, -0.28]4 studies · 271 participantsGRADE not reported
Oral mucositis severity
Topical zinc therapy (zinc sulfate, zinc oxide or zinc chloride mouthwash, paste, spray or gel) vs Control treatments (placebo, chlorhexidine, sodium bicarbonate, polyherbal, standard care) · 4 weeks after treatment initiation
SMD -1.24 [-2.53, 0.04]3 studies · 111 participantsGRADE not reported

1 including review in total.