Primary study · included by 2 reviews
Long-Term Effect of Xylitol Gum Use on Mutans Streptococci in Adults
Haresaku 2007 · Haresaku S., Hanioka T., Tsutsui A., et al. · Caries Research · 2007
doi:10.1159/000099318journal-article
Trial PICO
Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.
Results
Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Plaque quantity (plaque index or plaque weight) Sugar-free chewing gum (any polyol: xylitol, sorbitol, or maltitol), chewed regularly vs No sugar-free gum / no chewing gum (or gum-base control); no chewing · End of study (last reported time point; study durations 4 days to 2 years) | SMD -0.778 [-1.167, -0.390] | 7 studies | Ungraded |
Plaque quantity (plaque index or plaque weight) Sugar-free chewing gum (any polyol: xylitol, sorbitol, or maltitol), chewed regularly vs No sugar-free gum / no chewing gum (or gum-base control); no chewing · End of study (last reported time point; study durations 4 days to 2 years) | SMD -1.098 [-1.539, -0.656] | 7 studies | Ungraded |
Clinical Effects of Sugar Substitutes on Cariogenic Bacteria: A Systematic Review and Meta-Analysis.
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Change in Mutans streptococci (MS) count in dental plaque Xylitol (low-intensity sweetener/sugar alcohol) in food products (chewing gum, milk, candy, or tablets) vs No treatment (no gum / no intervention) · Post-consumption endpoint (trial durations 2 wk to 6 mo) | SMD -0.73 [-1.09, -0.37] | 5 studies · 308 participants | Ungraded |
2 including reviews in total.