Primary study · included by 1 review

Recurrent trigeminal neuralgia: long term outcome of repeat gamma knife radiosurgery

Gellner 2008 · Gellner V, Kurschel S, Kreil W, et al. · Journal of Neurology, Neurosurgery & Psychiatry · 2008

Included by

Repeat gamma knife radiosurgery for recurrent trigeminal neuralgia: a systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Gellner 2008 · Table 1; reference list

Outcome this study informs	Pooled effect	Evidence	Certainty
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient -0.0057	7 studies	GRADE not reported
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient -0.0004	8 studies	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient 0.0022	8 studies	GRADE not reported
Facial hypoesthesia after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS	Proportion (%) 39.04 [26.65, 51.42]	12 studies · 564 participants	GRADE not reported
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS	Proportion (%) 29.07 [22.68, 35.46]	14 studies · 1404 participants	GRADE not reported
BNI pain score I-III (favorable pain outcome) at latest follow-up Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · Latest available follow-up (median follow-up 14-74 months across studies)	Proportion (%) 61.94 [35.59, 82.74]	8 studies · 350 participants	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm) · After repeat GKRS	Proportion (%) 68.44 [58.44, 78.44]	12 studies · 1078 participants	GRADE not reported
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient -0.0109	9 studies	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient -0.0086	6 studies	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient 0.0047	8 studies	GRADE not reported
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient -0.0000	10 studies	GRADE not reported
Pain recurrence after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient 0.0035	10 studies	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient 0.0012	6 studies	GRADE not reported
Pain relief after repeat GKRS Repeat Gamma Knife radiosurgery (GKRS) vs No comparator (single-arm)	Meta-regression coefficient -0.0011	10 studies	GRADE not reported

1 including review in total.