evidencegaps
Primary study · included by 1 review

A multi‐centre randomized controlled trial comparing connective tissue graft with collagen matrix to increase soft tissue thickness at the buccal aspect of single implants: 3‐month results

Cosyn 2021 · Cosyn Jan, Eeckhout Célien, Christiaens Véronique, et al. · Journal of Clinical Periodontology · 2021

Included by

Comparative outcomes of xenogeneic collagen matrices and autogenous graft-based techniques to increase mucosal thickness and keratinised mucosa width at implant sites: are autologous grafts still the gold standard? A systematic review and meta-analysis of randomised clinical trials.
Non-Cochrane · intervention · 2026 · cited as Cosyn 2021 · Results, Study selection; Figures 2-4 and 6; reference list
Outcome this study informsPooled effectEvidenceCertainty
Increase in buccal mucosal thickness (MT), mm
Crosslinked xenogeneic collagen matrix (VCMX, Fibro-Gide) with bilaminar technique vs Subepithelial connective tissue graft (CTG) with bilaminar technique · 3 months
MD 0.02 [-0.17, 0.22]4 studies · 142 participantsGRADE not reported
Increase in buccal mucosal thickness (MT), mm
Xenogeneic collagen matrices (XCM*, non-crosslinked, and VCMX, crosslinked) with bilaminar technique vs Subepithelial connective tissue graft (CTG) with bilaminar technique · 3 months
MD 0.27 [0.12, 0.42]9 studies · 294 participantsGRADE not reported

1 including review in total.