Primary study · included by 1 review

An animal model of intrinsic dental erosion caused by gastro‐oesophageal reflux disease

Higo 2009 · Higo T, Mukaisho K, Ling Z‐Q, et al. · Oral Diseases · 2009

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review.
Non-Cochrane · aetiology · 2020 · cited as Higo 2009 · Results 'Experimental research'; Table 2; References [42]
Outcome this study informsPooled effectEvidenceCertainty
Dental erosion, alveolar bone destruction and oral/pharyngeal lesions
Surgically induced or chronic acid gastroesophageal reflux (experimental) vs Non-reflux control animals
Two rat-model studies found significantly higher rates of dental erosion, alveolar bone destruction and osteomyelitis (Higo) and shorter molar crown heights with dentin exposure, inflammatory infiltration and fibrosis…2 studiesUngraded

1 including review in total.