Primary study · included by 1 review

Disturbance in the Regulation of the Type of Collagen Synthesized in a Form of Osteogenesis Imperfecta

Meigel 1975 · MULLER Peter K., LEMMEN Christa, GAY Steffen, et al. · European Journal of Biochemistry · 1975

Included by

Post-translational modifications of collagen type I in osteogenesis imperfecta: Systematic review and meta-analysis.
Non-Cochrane · other · 2026 · cited as Meigel 1975 · Table 3; Supplementary material 2 (meta-analysis reference list)
Outcome this study informsPooled effectEvidenceCertainty
Hydroxyproline (HYP) percentage in collagen-I
OI collagen-I (patient-derived bone, fibroblast or dentine samples) vs Control (healthy) collagen-I
Printed in Figure 3A as 0.01 [ 0.03, 0.01] (signs not legible); I2 6.0%, tau2 0.00; test for subgroup difference QM 3.37, df 13 studies · 62 participantsGRADE not reported
Hydroxyproline (HYP) percentage in collagen-I
OI collagen-I (patient-derived bone, fibroblast or dentine samples) vs Control (healthy) collagen-I
Normalized mean difference 0.01 [-0.01, 0.03]14 studies · 79 participantsGRADE not reported
Hydroxyproline (HYP) percentage in collagen-I
OI collagen-I (patient-derived bone, fibroblast or dentine samples) vs Control (healthy) collagen-I
Normalized mean difference 0.00 [-0.02, 0.02]17 studies · 141 participantsGRADE not reported

1 including review in total.