Primary study · included by 1 review

Dental plaque formation and salivary mutans streptococci in schoolchildren after use of xylitol‐containing chewing gum

Holgerson et al. 2006 · HOLGERSON PERNILLA LIF, SJÖSTRÖM INGER, STECKSÉN‐BLICKS CHRISTINA, et al. · International Journal of Paediatric Dentistry · 2006

doi:10.1111/j.1365-263x.2006.00808.xjournal-article

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Clinical Effects of Sugar Substitutes on Cariogenic Bacteria: A Systematic Review and Meta-Analysis.

Non-Cochrane · intervention · 2024 · cited as Holgerson et al. 2006 · Table 2 (included studies, saliva); Figure 7 (xylitol vs sorbitol, saliva); ref 53

Outcome this study informs	Pooled effect	Evidence	Certainty
Change in Mutans streptococci (MS) count in saliva Xylitol (low-intensity sweetener/sugar alcohol) in food products (chewing gum, milk, candy, or tablets) vs Sorbitol (low-intensity sweetener) · Post-consumption endpoint (varied durations across trials)	SMD -0.16 [-0.44, 0.12]	2 studies · 201 participants	Ungraded

1 including review in total.