Primary study · included by 1 review
Effect of the addition of Chitosan and TiO <sub>2</sub> nanoparticles on antibacterial properties of an orthodontic composite in fixed orthodontic treatment: a randomized clinical trial study
Farzanegan et al. 2021 · Farzanegan Fahimeh, Shahabi Mostafa, Niazi Ahmad Ehsan, et al. · Biomedical Physics & Engineering Express · 2021
doi:10.1088/2057-1976/ac0609journal-article
Trial PICO
Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.
Results
Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Streptococcus mutans count Transbond XT with 1% chitosan and 1% TiO2 nanoparticles vs Transbond XT adhesive · 1 day, 2 months, and 6 months after bonding | Experimental group: significant decrease in S. mutans count was observed at the time points of 1 day, 2 months, and 6 months for both maxillary lateral incisor (p = 0.01) and maxillary second premolar teeth (p = 0.001). | 1 study · 24 participants | Ungraded |
Enamel demineralization / white spot lesion prevention (DIAGNOdent, enamel mineral content) Farzanegan 2021 = Transbond XT + 1% chitosan + 1% TiO2 (co-intervention); Mollabashi 2022 = TiO2-only composite (1 wt%) vs Conventional adhesive/composite (Transbond XT) · 1 day to 6 months | Two RCTs (Farzanegan 2021 n=24; Mollabashi 2022 n=40): Mollabashi reported DIAGNOdent readings significantly lower on the TiO2 side than the control side (p<0.001); Farzanegan reported no significant difference in… | 2 studies · 64 participants | Ungraded |
1 including review in total.