Primary study · included by 1 review

A Comparison of Different Volumes of Articaine for Inferior Alveolar Nerve Block for Molar Teeth with Symptomatic Irreversible Pulpitis

Abazarpoor 2015 · Abazarpoor Ramin, Parirokh Masoud, Nakhaee Nouzar, et al. · Journal of Endodontics · 2015

Included by

Evaluation of the effectiveness of local anesthesia approaches for symptomatic irreversible pulpitis: a systematic review and meta-analysis.

Non-Cochrane · intervention · 2025 · cited as Abazarpoor 2015 · Table 1; Figure 3

Outcome this study informs	Pooled effect	Evidence	Certainty
Anesthesia success (adequate pain control during endodontic treatment) Modified anesthetic protocols (articaine, supplemental infiltrations, additives, increased volume) vs Conventional inferior alveolar nerve block (IANB) with 2% lidocaine with epinephrine · During endodontic treatment	OR 3.62 [2.91, 4.27]	3 studies	GRADE not reported
Anesthesia success (adequate pain control during endodontic treatment) Modified anesthetic protocols (articaine, supplemental infiltrations, additives, increased volume) vs Conventional inferior alveolar nerve block (IANB) with 2% lidocaine with epinephrine · During endodontic treatment	OR 3.34 [2.49, 4.48]	16 studies	High
Anesthesia success (adequate pain control during endodontic treatment) Modified anesthetic protocols (articaine, supplemental infiltrations, additives, increased volume) vs Conventional inferior alveolar nerve block (IANB) with 2% lidocaine with epinephrine · During endodontic treatment	OR 3.26 [1.70, 6.28]	3 studies	GRADE not reported
Anesthesia success (adequate pain control during endodontic treatment) Modified anesthetic protocols (articaine, supplemental infiltrations, additives, increased volume) vs Conventional inferior alveolar nerve block (IANB) with 2% lidocaine with epinephrine · During endodontic treatment	OR 3.36 [1.44, 7.85]	3 studies	GRADE not reported
Anesthesia success (adequate pain control during endodontic treatment) Modified anesthetic protocols (articaine, supplemental infiltrations, additives, increased volume) vs Conventional inferior alveolar nerve block (IANB) with 2% lidocaine with epinephrine · During endodontic treatment	OR 4.31 [3.59, 5.17]	6 studies	High
Anesthesia success (adequate pain control during endodontic treatment) Modified anesthetic protocols (articaine, supplemental infiltrations, additives, increased volume) vs Conventional inferior alveolar nerve block (IANB) with 2% lidocaine with epinephrine · During endodontic treatment	OR 3.79 [3.24, 4.44]	16 studies	GRADE not reported

1 including review in total.