Primary study · included by 1 review

Association of pre-eclampsia with or without superimposed chronic hypertension in pregnant women with the risk of congenital abnormalities in their offspring: a population-based case–control study

Banhidy 2012 · Bánhidy Ferenc, Szilasi Maria, Czeizel Andrew E. · European Journal of Obstetrics & Gynecology and Reproductive Biology · 2012

Included by

Outcome this study informsPooled effectEvidenceCertainty
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.19 [1.01, 1.38]4 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.11 [1.05, 1.17]5 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.74 [1.30, 2.32]11 studiesGRADE not reported
Cleft lip and/or palate (CLP) in offspring
Maternal hypertension (any type) vs No maternal hypertension
OR 1.69 [1.28, 2.23]11 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.38 [1.21, 1.54]7 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.33 [1.23, 1.42]10 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.64 [1.16, 2.12]2 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.25 [1.08, 1.42]5 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.47 [1.15, 1.78]NRGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.36 [1.24, 1.48]3 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.33 [1.24, 1.42]2 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.19 [1.04, 1.34]7 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.45 [1.27, 1.67]12 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.59 [1.324, 2.03]11 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.42 [1.23, 1.60]5 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.17 [0.95, 1.39]2 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.39 [1.23, 1.56]9 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.37 [1.25, 1.48]4 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.46 [1.18, 1.81]11 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.24 [1.03, 1.46]10 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.41 [1.18, 1.63]3 studiesGRADE not reported
Cleft lip and/or palate (CLP) in offspring
Maternal hypertension (any type) vs No maternal hypertension
OR 1.62 [1.25, 2.11]11 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.94 [0.63, 3.25]10 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.59 [1.24, 2.03]11 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.37 [1.21, 1.53]2 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.35 [1.25, 1.45]10 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 4.73 [2.71, 6.76]2 studiesGRADE not reported
Cleft lip and/or palate (CLP) in offspring
Maternal hypertension (any type) vs No maternal hypertension
OR 1.66NRGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.38 [1.27, 1.48]8 studiesGRADE not reported
Cleft lip and/or palate (CLP) in offspring
Maternal hypertension (any type) vs No maternal hypertension
OR 1.33 [1.24, 1.42]10 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.35 [1.24, 1.46]7 studiesGRADE not reported
Cleft lip and/or palate (CLP) in offspring
Maternal hypertension (any type) vs No maternal hypertension
OR 1.67 [1.25, 2.22]11 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.14 [1.09, 1.19]3 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.49 [1.18, 1.88]11 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.41 [1.03, 1.79]2 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.29 [1.13, 1.45]4 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.22 [0.87, 1.58]2 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.44 [1.26, 1.64]12 studies · 4407254 participantsGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.22 [0.87, 1.58]3 studiesGRADE not reported
Cleft lip and/or palate (CLP) in offspring
Maternal hypertension (any type) vs No maternal hypertension
OR 1.61 [1.22, 2.13]11 studiesGRADE not reported
Cleft lip and palate (CLP) in offspring
Any maternal hypertension (pre-pregnancy, gestational, preeclampsia, chronic) vs No maternal hypertension
OR 1.42 [1.23, 1.60]8 studiesGRADE not reported

1 including review in total.