Primary study · included by 1 review

Dental and oropharyngeal lesions in rats with chronic acid reflux esophagitis

Shimazu 2018 · Shimazu Rintaro, Yamamoto Mihoko, Minesaki Akimichi, et al. · Auris Nasus Larynx · 2018

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review.
Non-Cochrane · aetiology · 2020 · cited as Shimazu 2018 · Results 'Experimental research'; Table 2; References [43]
Outcome this study informsPooled effectEvidenceCertainty
Dental erosion, alveolar bone destruction and oral/pharyngeal lesions
Surgically induced or chronic acid gastroesophageal reflux (experimental) vs Non-reflux control animals
Two rat-model studies found significantly higher rates of dental erosion, alveolar bone destruction and osteomyelitis (Higo) and shorter molar crown heights with dentin exposure, inflammatory infiltration and fibrosis…2 studiesUngraded

1 including review in total.