Primary study · included by 1 review

Effectiveness of a sealant compared with no sealant in preventing enamel demineralization in patients with fixed orthodontic appliances: A prospective clinical trial

O'Reilly 2013 · O'Reilly Maria T., De Jesús Viñas Jaime, Hatch John P. · American Journal of Orthodontics and Dentofacial Orthopedics · 2013

Trial PICO

Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.

Results

Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.

Included by

Efficacy of sealants and bonding materials during fixed orthodontic treatment to prevent enamel demineralization: a systematic review and meta-analysis.
Non-Cochrane · intervention · 2021 · cited as O'Reilly 2013 · Supplementary Table S3 (included studies); Reference [41]; Fig. 3
Outcome this study informsPooled effectEvidenceCertainty
Initiation of white spot lesions (WSL), visual-tactile assessment
Sealant/coating agent WITH fluoride release applied to teeth with fixed appliances vs No sealant (untreated control teeth) · 3-27 months follow-up
RR 0.69 [0.46, 1.05]3 studies · 1467 participantsUngraded
Incidence of new white spot lesions by visual-tactile assessment
Sealant vs No sealant · 3 to 27 months
RR 0.70 [0.53, 0.93]6 studies · 2314 participantsVery low
Initiation of white spot lesions (WSL), visual-tactile assessment
Sealant/coating agent WITHOUT fluoride release applied to teeth with fixed appliances vs No sealant (untreated control teeth) · 3-27 months follow-up
RR 0.69 [0.49, 0.97]3 studies · 847 participantsUngraded
Initiation of white spot lesions (WSL), visual-tactile assessment
Sealant or coating agent (with or without fluoride release) applied to teeth with fixed appliances vs No sealant (untreated control teeth) · 3-27 months follow-up
RR 0.70 [0.53, 0.93]6 studies · 2314 participantsVery low

1 including review in total.