Primary study · included by 1 review

Local application of curcumin-loaded nanoparticles as an adjunct to scaling and root planing in periodontitis: Randomized, placebo-controlled, double-blind split-mouth clinical trial

Perez-Pacheco 2021 · Pérez-Pacheco Cindy Grace, Fernandes Natalie Ap. Rodrigues, Primo Fernando Lucas, et al. · Clinical Oral Investigations · 2020

Included by

Local curcumin/turmeric-derived delivery adjunctive to scaling and root planing for periodontitis: a systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Perez-Pacheco 2021 · References 25-55; Supplementary Table S1 and S3
Outcome this study informsPooled effectEvidenceCertainty
Probing pocket depth (PPD) reduction, mean difference in mm (negative favors curcumin)
Subgingivally delivered curcumin/turmeric-derived formulation (gel, chip, strip, in situ gel, nanoparticle) adjunctive to SRP vs Inactive control (SRP alone, placebo or empty vehicle) · Longest available follow-up
MD -0.46 [-0.68, -0.24]15 studiesLow

1 including review in total.