Primary study · included by 1 review

Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy

Mohammadi 2022 · Mohammadi Fateme, Oshvandi Khodayar, Kamallan Seyed Ramesh, et al. · Nursing Open · 2022

Included by

Efficacy of topical application of zinc compounds for oral mucosal diseases: A systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Mohammadi 2022 · Figure 4; reference list
Outcome this study informsPooled effectEvidenceCertainty
Oral mucositis severity
Topical zinc therapy (zinc sulfate, zinc oxide or zinc chloride mouthwash, paste, spray or gel) vs Control treatments (placebo, chlorhexidine, sodium bicarbonate, polyherbal, standard care) · 3 weeks after treatment initiation
MD -0.41 [-0.79, -0.03]4 studies · 271 participantsGRADE not reported
Oral mucositis severity
Topical zinc therapy (zinc sulfate, zinc oxide or zinc chloride mouthwash, paste, spray or gel) vs Control treatments (placebo, chlorhexidine, sodium bicarbonate, polyherbal, standard care) · 2 weeks after treatment initiation
MD -0.46 [-0.63, -0.28]4 studies · 271 participantsGRADE not reported

1 including review in total.