Primary study · included by 1 review
Maternal antihypertensive medication use and selected birth defects in the National Birth Defects Prevention Study
Fisher 2018 · Fisher Sarah C., Van Zutphen Alissa R., Werler Martha M., et al. · Birth Defects Research · 2018
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Cleft lip and palate (CLP) in offspring Maternal antihypertensive medication use in pregnancy vs No antihypertensive medication | OR 1.45 [0.98, 2.17] | 5 studies | GRADE not reported |
Cleft lip and/or palate (CLP) in offspring Maternal antihypertensive medication use during pregnancy vs No maternal antihypertensive medication use | OR 1.47 [1.01, 2.13] | 5 studies · 606025 participants | GRADE not reported |
Cleft lip and palate (CLP) in offspring Maternal antihypertensive medication use in pregnancy vs No antihypertensive medication | OR 2.37 [0.93, 6.04] | 5 studies · 606025 participants | GRADE not reported |
Cleft lip and palate (CLP) in offspring Maternal antihypertensive medication use in pregnancy vs No antihypertensive medication | OR 1.69 [0.40, 7.07] | 3 studies | GRADE not reported |
1 including review in total.