Non-Cochrane · intervention · PM42782925

Clinical and Esthetic Outcomes of Vestibular Socket Therapy: A Systematic Review and Meta-Analysis.

Soliman Yasser Sherif, Krockow Nadine Gräfin von, Hassanein Fatma E A, et al. · Dentistry journal · 2026 · PubMed · doi:10.3390/dj14090538

Findings

8 findings

Population
Adults with non-restorable anterior maxillary teeth and thin or deficient facial socket wallsVestibular socket therapy with immediate implant placementEarly implant placement with contour augmentation, partial extraction therapy, or dual-zone graftingApical buccal bone plate thickness
6–12 months · Egypt; private implant practices and university dental outpatient clinics · Random effects
MD 0.19 [-0.48, 0.87]
Very low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
3 studies · 89 participants
Adults with non-restorable anterior maxillary teeth and thin or deficient facial socket wallsVestibular socket therapy with immediate implant placementEarly implant placement with contour augmentation, partial extraction therapy, or dual-zone graftingMid-root buccal bone plate thickness
6–12 months · Egypt; private implant practices and university dental outpatient clinics · Random effects
MD 0.32 [-0.45, 1.09]
Very low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
3 studies · 89 participants
Adults with non-restorable anterior maxillary teeth and thin or deficient facial socket wallsVestibular socket therapy with immediate implant placementEarly implant placement with contour augmentation, partial extraction therapy, or dual-zone graftingCrestal buccal bone plate thickness
6–12 months · Egypt; private implant practices and university dental outpatient clinics · Random effects
MD 0.24 [-0.13, 0.61]
Very low
Downgraded: risk of bias, imprecision, publication bias
3 studies · 89 participants
Adults with non-restorable anterior maxillary teeth and thin or deficient facial socket wallsVestibular socket therapy with immediate implant placementEarly implant placement with contour augmentation, partial extraction therapy, or dual-zone graftingCrestal buccal bone plate thickness
6–12 months · Egypt; private implant practices and university dental outpatient clinics · Common effect
MD 0.33 [0.09, 0.56]
GRADE not reported
3 studies · 89 participants
Adults with non-restorable anterior maxillary teeth and thin or deficient facial socket wallsVestibular socket therapy with immediate implant placementEarly implant placement with contour augmentation, partial extraction therapy, or dual-zone graftingMid-root buccal bone plate thickness
6–12 months · Egypt; private implant practices and university dental outpatient clinics · Common effect
MD 0.43 [0.14, 0.73]
GRADE not reported
3 studies · 89 participants
Adults with non-restorable anterior maxillary teeth and thin or deficient facial socket wallsVestibular socket therapy with immediate implant placementEarly implant placement with contour augmentation, partial extraction therapy, or dual-zone graftingApical buccal bone plate thickness
6–12 months · Egypt; private implant practices and university dental outpatient clinics · Common effect
MD 0.23 [-0.08, 0.53]
GRADE not reported
3 studies · 89 participants
Adults receiving implants in compromised or thin-walled fresh extraction sockets in the maxillary esthetic zone (all arms of the 7 included RCTs)Immediate implant placement with vestibular socket therapy (all trial arms aggregated, including comparator arms)None (single-group aggregate across trials)Postoperative complications (shield exposure, peri-implantitis, wound dehiscence, membrane exposure)
Final follow-up of each trial (6-12 months) · Private implant practices and university dental outpatient clinics, Egypt
Proportion (%) 0
GRADE not reported
7 studies · 186 participants
Adults receiving implants in maxillary esthetic zoneVestibular socket therapy and comparator protocols across trial armsNoneImplant survival
Final follow-up · Egypt
Proportion 0.995
GRADE not reported
7 studies · 186 participants

Included primary studies 14

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Elaskary 2022a
Immediate implant placement utilizing vestibular socket therapy versus early implant placement with contour augmentation for…
DOI:10.1111/cid.13120
2022this review onlynot statednot extracted yet
ElAskary 2022a
Immediate implant placement utilizing vestibular socket therapy versus early implant placement with contour augmentation for…
PMID:35811090
2022this review onlynot statednot extracted yet
Elaskary 2022b
Does Grafting the Jumping Gap in Immediately Placed Anterior Implants Using Vestibular Socket Therapy Influence the Labial Bone Thickness?
DOI:10.1016/j.joms.2022.05.001
2022this review onlynot statednot extracted yet
ElAskary 2022b
Does Grafting the Jumping Gap in Immediately Placed Anterior Implants Using Vestibular Socket Therapy Influence the Labial Bone Thickness?
PMID:35688272
2022this review onlynot statednot extracted yet
Elaskary 2023
Immediate Implant Placement in Intact Fresh Extraction Sockets Using Vestibular Socket Therapy Versus Partial Extraction Therapy in the…
DOI:10.11607/jomi.9973
2023this review onlynot statednot extracted yet
ElAskary 2023
Immediate Implant Placement in Intact Fresh Extraction Sockets Using Vestibular Socket Therapy Versus Partial Extraction Therapy in the…
PMID:37279214
2023this review onlynot statednot extracted yet
Elaskary 2024
The bone shielding versus dual‐zone concept in treating thin‐walled fresh extraction sockets with immediate implant placement: Soft and…
DOI:10.1111/cid.13275
2023this review onlynot statednot extracted yet
ElAskary 2024
The bone shielding versus dual-zone concept in treating thin-walled fresh extraction sockets with immediate implant placement: Soft and…
PMID:37669913
2024this review onlynot statednot extracted yet
Ellithy 2024
Immediate implant placement in compromised extraction sockets using vestibular socket therapy with acellular dermal matrix versus…
DOI:10.1007/s00784-024-06065-8
2024this review onlynot statednot extracted yet
Ellithy 2024
Immediate implant placement in compromised extraction sockets using vestibular socket therapy with acellular dermal matrix versus…
PMID:39604639
2024this review onlynot statednot extracted yet
Ghallab 2023
A novel atraumatic extraction technique using vestibular socket therapy for immediate implant placement: a randomized controlled clinical…
DOI:10.1007/s10006-022-01089-4
2022this review onlynot statednot extracted yet
Ghallab 2023
A novel atraumatic extraction technique using vestibular socket therapy for immediate implant placement: a randomized controlled clinical…
PMID:35718834
2023this review onlynot statednot extracted yet
Hamed 2023
Effect of three different grafting materials on immediate implant placement using vestibular socket therapy in class II extraction sockets…
DOI:10.1186/s12903-023-03345-9
2023this review onlynot statednot extracted yet
Hamed 2023
Effect of three different grafting materials on immediate implant placement using vestibular socket therapy in class II extraction sockets…
PMID:37658342
2023this review onlynot statednot extracted yet

Review question

ElementPlanned (methods)Found (results)
PopulationAdults with non-restorable single teeth in the esthetic zone with thin or deficient labial bone walls covered by soft tissue (compromised fresh extraction sockets)186 adults in 7 RCTs (Egypt; ages 18-58); Type II deficient sockets (n=4), intact thin-walled Type I sockets (n=2), Type II extraction-technique trial (n=1)
InterventionVestibular socket therapy with immediate implant placementVST with immediate implant placement (n=7; 15 intervention arms)
ComparisonAny recognized socket-management approach at the time of implant placement (conventional immediate or early implant placement techniques, including PET and early placement with contour augmentation)Early placement with contour augmentation (n=1); partial extraction therapy (n=1); dual-zone grafting (n=1); within-VST variants: conventional incisal extraction (n=1), ungrafted jumping gap (n=1), alternative grafting materials (n=1), connective tissue graft vs acellular dermal matrix (n=1)
OutcomesPrimary: final buccal bone plate thickness (CBCT; crestal, mid-implant, apical). Secondary: implant survival, soft tissue stability, mid-facial recession, papilla position, peri-implant soft tissue contour, Pink Esthetic Score; patient-reported satisfaction and postoperative experience when availableFinal buccal bone plate thickness crestal, mid-root, apical (n=3 pooled); implant survival (n=7); postoperative complications (n=7); mid-facial recession (n=4); papilla change (n=3); Pink Esthetic Score (n=4); probing depth (n=1); mucosal thickness (n=1)
Study designsRandomized controlled trials published from 2020Randomized controlled trials (n=7)
TimingBuccal bone thickness 6-12 months; implant survival 12-24 months6-12 months

AMSTAR 2 items

Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.

ItemExtractor AExtractor BAgree
1Research question includes PICO componentsYesYesyes
2Protocol established before the reviewcriticalYesPartial Yesno
3Choice of study designs explainedNoYesno
4Comprehensive literature searchcriticalPartial YesYesno
5Study selection in duplicateYesYesyes
6Data extraction in duplicateYesYesyes
7List of excluded studies with reasonscriticalNoNoyes
8Included studies described in detailYesYesyes
9Risk of bias assessed satisfactorilycriticalRCT: Yes · NRSI: N/ARCT: Yes · NRSI: N/Ayes
10Funding of included studies reportedNoNoyes
11Appropriate meta-analysis methodscriticalRCT: Yes · NRSI: N/ARCT: Yes · NRSI: N/Ayes
12Impact of risk of bias on the pooled resultsNoNoyes
13Risk of bias accounted for in interpretationcriticalYesYesyes
14Heterogeneity explainedYesYesyes
15Publication bias investigatedcriticalYesNono
16Conflicts of interest reportedYesYesyes
OverallLowCritically Lowno