Non-Cochrane · intervention · PM42578185
Long-term Outcomes of Tooth-implant Supported Prostheses - A Systematic Review and Meta-analysis.
Gupta Abhishek Kumar, Dhandai Gomati, Anitha G, et al. · Annals of maxillofacial surgery · 2026 · PubMed · doi:10.4103/ams.ams_160_25
Findings
Population Partially edentulous patients with fixed tooth-implant supported prostheses (TISP)
12 findings
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Incidence of framework decementation 12 to 72 months follow-up | Mean incidence (%) 1.6 [0.6, 2.7] GRADE not reported 4 studies |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Incidence of porcelain fracture 12 to 72 months follow-up | Mean incidence (%) 2.8 [1.0, 4.6] GRADE not reported 5 studies |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Prosthesis success (absence of biological or mechanical complications) 12 to 72 months follow-up · Connector type: non-rigid | Average success rate (%) 91.0 GRADE not reported 5 studies |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Incidence of tooth intrusion 12 to 72 months follow-up | Mean incidence (%) 5.4 [3.1, 7.2] GRADE not reported 6 studies |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Prosthesis survival 12 to 72 months follow-up · Connector type: rigid | Average survival rate (%) 90.9 GRADE not reported 5 studies |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Incidence of screw loosening 12 to 72 months follow-up | Mean incidence (%) 4.1 [1.2, 6.3] GRADE not reported 7 studies |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Prosthesis survival 12 to 72 months follow-up | Pooled proportion 0.917 [0.89, 0.93] GRADE not reported 12 studies · 782 participants |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Prosthesis survival 12 to 72 months follow-up · Connector type: non-rigid | Average survival rate (%) 93.7 GRADE not reported 5 studies |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Incidence of marginal bone loss greater than 1 mm 12 to 72 months follow-up | Mean incidence (%) 3.9 [1.8, 6.2] GRADE not reported 5 studies |
| Tooth-implant supported fixed prostheses | None (single-arm pooled proportion) | Prosthesis success (absence of biological or mechanical complications) 12 to 72 months follow-up · Connector type: rigid | Average success rate (%) 88.9 GRADE not reported 5 studies |
| Non-rigid connectors | Rigid connectors | Prosthesis survival 12 to 72 months follow-up · Fig 2b pooled estimate (10 studies, hazard ratio scale) | HR 0.91 [0.90, 0.93] GRADE not reported 10 studies |
| Non-rigid connectors | Rigid connectors | Prosthesis survival 12 to 72 months follow-up | RD 0.026 [-0.008, 0.057] GRADE not reported 10 studies |
Included primary studies 21
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Chrcanovic 2020 Analysis of technical complications and risk factors for failure of combined tooth‐implant‐supported fixed dental prostheses DOI:10.1111/cid.12927 | 2020 | this review only | not stated | not extracted yet |
| Chrcanovic 2020 Analysis of technical complications and risk factors for failure of combined tooth-implant-supported fixed dental prostheses. PMID:32524744 | 2020 | this review only | not stated | not extracted yet |
| Dahlgren 2024 Long‐term outcomes and complication rates of tooth‐implant‐supported fixed dental prostheses: A retrospective cohort study DOI:10.1111/jopr.13982 | 2024 | this review only | not stated | not extracted yet |
| Dahlgren 2024 Long-term outcomes and complication rates of tooth-implant-supported fixed dental prostheses: A retrospective cohort study. PMID:39659027 | 2025 | this review only | not stated | not extracted yet |
| Ekren 2024 Clinical Evaluation of Mandibular Posterior Three-Unit Combined Tooth-/Implant-Supported Fixed Partial Dentures: Controlled Prospective… PMID:37768141 | 2024 | this review only | not stated | not extracted yet |
| Guarnieri 2019 Long-Term Outcomes of Tooth-Implant-Supported Rehabilitation of Periodontally Compromised and Treated Patients Refusing Bone Grafting… DOI:10.1097/id.0000000000000847 | 2019 | this review only | not stated | not extracted yet |
| Guarnieri 2019 Long-Term Outcomes of Tooth-Implant-Supported Rehabilitation of Periodontally Compromised and Treated Patients Refusing Bone Grafting… PMID:31219945 | 2019 | this review only | not stated | not extracted yet |
| Hashemi 2024 Stress Analysis of Endodontically Treated Tooth–Implant Different Connectors Designs in Maxillary Posterior Region: A Finite Element… DOI:10.1055/s-0043-1772780 | 2023 | this review only | not stated | not extracted yet |
| Hashemi 2024 Stress Analysis of Endodontically Treated Tooth-Implant Different Connectors Designs in Maxillary Posterior Region: A Finite Element… PMID:37848070 | 2024 | this review only | not stated | not extracted yet |
| Jivraj 2018 Connecting implants to teeth DOI:10.1038/sj.bdj.4814260 | 2006 | this review only | not stated | not extracted yet |
| Jivraj 2018 Connecting implants to teeth. PMID:17128232 | 2006 | this review only | not stated | not extracted yet |
| La Monaca 2021 Survival and complication rates of tooth-implant versus freestanding implant supporting fixed partial prosthesis: a systematic review and… DOI:10.2186/jpr.jpor_2019_494 | 2021 | this review only | not stated | not extracted yet |
| La Monaca 2021 Survival and complication rates of tooth-implant versus freestanding implant supporting fixed partial prosthesis: a systematic review and… PMID:32938874 | 2021 | this review only | not stated | not extracted yet |
| Lindh 2017 Tooth-implant supported fixed prostheses: a retrospective multicenter study. PMID:11508086 | 2001 | this review only | not stated | not extracted yet |
| Naguib 2023 Effect of non‐rigid connector on the stress distribution of tooth‐implant supported fixed prostheses using different implant length and… DOI:10.1111/jopr.13702 | 2023 | this review only | not stated | not extracted yet |
| Naguib 2023 Effect of non-rigid connector on the stress distribution of tooth-implant supported fixed prostheses using different implant length and… PMID:37184094 | 2023 | this review only | not stated | not extracted yet |
| Narde 2024 Evaluation and assessment of the survival of tooth implant supported prosthesis in tooth and implant supported rehabilitation cases with… DOI:10.1186/s12903-024-04117-9 | 2024 | this review only | not stated | not extracted yet |
| Narde 2024 Evaluation and assessment of the survival of tooth implant supported prosthesis in tooth and implant supported rehabilitation cases with… PMID:38519932 | 2024 | this review only | not stated | not extracted yet |
| Rammelsberg 2021 Effect of prosthetic restoration on implant survival and success DOI:10.1111/clr.12974 | 2016 | this review only | not stated | not extracted yet |
| Rammelsberg 2021 Effect of prosthetic restoration on implant survival and success. PMID:27624214 | 2017 | this review only | not stated | not extracted yet |
| Taneja 2023 Survival of tooth-implant connections: A systematic review and meta-analysis. PMID:37861608 | 2023 | this review only | not stated | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Partially edentulous patients rehabilitated with tooth-implant supported prostheses | 732 patients, 840 prostheses (12 studies); elderly, periodontally and systemically compromised subgroups described |
| Intervention | Fixed prostheses supported by teeth and implants with various connector configurations and framework materials | Tooth-implant supported prostheses with rigid or non-rigid connectors and metal-ceramic or zirconia frameworks |
| Comparison | Rigid vs non-rigid connectors; zirconia vs metal-based frameworks; systemically or periodontally compromised vs healthy populations | Rigid vs non-rigid connectors (10 studies); zirconia vs metal frameworks (12 studies) |
| Outcomes | Prosthesis survival, success rate, incidence of biomechanical (mechanical and biological) complications | Survival (pooled 0.91, n=12); success 86% to 94%; tooth intrusion, screw loosening, porcelain fracture, decementation, marginal bone loss |
| Study designs | Clinical studies (RCTs and observational) with at least 12 months follow-up | Prospective cohorts, retrospective analyses, RCTs and mixed-method designs |
| Timing | At least 12 months follow-up | 12 to 72 months follow-up |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | Partial Yes | Partial Yes | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | Partial Yes | Partial Yes | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | Yes | Yes | yes |
| 7List of excluded studies with reasonscritical | No | No | yes |
| 8Included studies described in detail | Partial Yes | Partial Yes | yes |
| 9Risk of bias assessed satisfactorilycritical | RCT: No · NRSI: Partial Yes | NRSI: Yes · RCT: No | no |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: Partial Yes · NRSI: Partial Yes | NRSI: No · RCT: No | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | Yes | Yes | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | Yes | Yes | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Critically Low | Critically Low | yes |