Non-Cochrane · other · PM42519815
Global prevalence and guideline adherence of antibiotic prescribing in dental implant surgery: A systematic review and meta-analysis.
Almadhoon Hossam, Alshayyah Madiha, Abu Eida Mohammed, et al. · The Japanese dental science review · 2026 · PubMed · doi:10.1016/j.jdsr.2026.07.001
Findings
73 findings
| Population | ||||
|---|---|---|---|---|
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: France | Pooled prevalence (%) 24.9 [20.6, 29.4] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by patient high-risk condition Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · High-risk condition: Diabetes mellitus | Pooled prevalence (%) 59.8 [1.8, 100.0] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 531 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by procedure Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Procedure: Impression taking | Pooled prevalence (%) 2.7 [0.0, 22.6] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 643 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by implant complexity Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Implant complexity: Simple implant placement | Pooled prevalence (%) 71.6 [55.3, 85.5] Very low Downgraded: risk of bias, imprecision, inconsistency 10 studies · 1801 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Germany | Pooled prevalence (%) 74.8 [65.9, 82.7] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Croatia | Pooled prevalence (%) 59.9 [52.1, 67.4] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Sweden | Pooled prevalence (%) 81.3 [0.0, 100.0] GRADE not reported 2 studies |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by implant complexity Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Implant complexity: Multiple/complex implant placement | Pooled prevalence (%) 80.2 [52.2, 97.7] Very low Downgraded: risk of bias, imprecision, inconsistency 6 studies · 1061 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) | Pooled prevalence (%) 61.3 [53.4, 68.8] Very low Downgraded: risk of bias, inconsistency 24 studies · 5013 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by implant complexity Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Implant complexity: Compromised implant placement | Pooled prevalence (%) 97.3 [83.5, 100.0] Very low Downgraded: risk of bias 2 studies · 361 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by patient high-risk condition Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · High-risk condition: Inadequate oral hygiene | Pooled prevalence (%) 32.5 [0.0, 84.9] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 445 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Netherlands | Pooled prevalence (%) 43.7 [35.9, 51.7] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: United Kingdom | Pooled prevalence (%) 53.1 [13.5, 90.5] GRADE not reported 3 studies |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by patient high-risk condition Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · High-risk condition: Cardiovascular disease | Pooled prevalence (%) 73.8 [57.1, 87.7] Very low Downgraded: risk of bias, imprecision, inconsistency 11 studies · 1536 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by procedure Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Procedure: Sinus lifting | Pooled prevalence (%) 81.2 [50.9, 98.7] Very low Downgraded: risk of bias, imprecision, inconsistency 6 studies · 1204 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by patient high-risk condition Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · High-risk condition: Implant failure history | Pooled prevalence (%) 38.5 [0.0, 100.0] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 289 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by procedure Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Procedure: Prosthetic placement | Pooled prevalence (%) 2.9 [0.0, 24.1] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 643 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Time period: Studies from 2008 to 2012 | Pooled prevalence (%) 77.6 [49.2, 96.5] GRADE not reported Studies not reported |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Time period: Studies published 2015 to 2022 | Pooled prevalence (%) 58.9 [49.5, 68.0] GRADE not reported Studies not reported |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by procedure Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Procedure: Healing abutment insertion | Pooled prevalence (%) 8.6 [2.3, 18.1] Very low Downgraded: risk of bias, inconsistency 3 studies · 645 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by patient high-risk condition Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · High-risk condition: Artificial joints | Pooled prevalence (%) 64.2 [27.6, 93.3] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 532 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Switzerland | Pooled prevalence (%) 64.4 [54.0, 74.1] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of routine antibiotic prescribing by timing relative to surgery Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Timing: Pre- and post-operative | Pooled prevalence (%) 52.6 [38.4, 66.5] Very low Downgraded: risk of bias, imprecision, inconsistency 12 studies · 1782 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by patient high-risk condition Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · High-risk condition: Immunodeficiency disorders | Pooled prevalence (%) 66.4 [12.0, 100.0] Very low Downgraded: risk of bias, imprecision, inconsistency 4 studies · 540 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Saudi Arabia | Pooled prevalence (%) 46.0 [19.1, 74.3] GRADE not reported 3 studies |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Spain | Pooled prevalence (%) 73.9 [0.0, 100.0] GRADE not reported 2 studies |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Iraq | Pooled prevalence (%) 56.8 [52.3, 61.2] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Jordan | Pooled prevalence (%) 49.4 [41.9, 56.9] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by patient high-risk condition Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · High-risk condition: Smoking | Pooled prevalence (%) 57.4 [7.9, 98.2] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 587 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Portugal | Pooled prevalence (%) 64.2 [57.5, 70.7] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Italy | Pooled prevalence (%) 66.5 [21.6, 98.0] GRADE not reported 3 studies |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of antibiotic prescribing by procedure Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Procedure: Bone augmentation | Pooled prevalence (%) 80.7 [11.0, 100.0] Very low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 622 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of routine antibiotic prescribing by timing relative to surgery Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Timing: Post-operative only | Pooled prevalence (%) 22.6 [12.5, 34.8] Very low Downgraded: risk of bias, imprecision, inconsistency 12 studies · 1786 participants |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: India | Pooled prevalence (%) 80.2 [1.1, 100.0] GRADE not reported 2 studies |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of dentist-reported routine antibiotic prescribing Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Country: Australia | Pooled prevalence (%) 55.3 [39.2, 70.9] GRADE not reported 1 study |
| Dentists who perform dental implant surgery (dentist surveys) | Routine antibiotic prescribing for dental implant surgery | None | Prevalence of routine antibiotic prescribing by timing relative to surgery Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Timing: Pre-operative only | Pooled prevalence (%) 16.8 [7.8, 28.4] Very low Downgraded: risk of bias, imprecision, inconsistency 12 studies · 1790 participants |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic regimens by grouped category Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Short (1-3 days) | Pooled proportion (%) 12.1 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Phenoxymethylpenicillin | Pooled proportion (%) 3.2 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic regimens by grouped category Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Moderate (4-5 days) | Pooled proportion (%) 37.4 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin 800 mg | Pooled proportion (%) 3.3 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 10 days | Pooled proportion (%) 2.9 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Metronidazole | Pooled proportion (%) 0.9 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 4 days | Pooled proportion (%) 4.0 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 3 days | Pooled proportion (%) 7.1 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Ofloxacin | Pooled proportion (%) 0.7 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin + metronidazole | Pooled proportion (%) 1.7 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin + cloxacillin | Pooled proportion (%) 0.6 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Timing of pre-operative antibiotic administration Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 2-12 hours prior | Pooled proportion (%) 1.0 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 2 days | Pooled proportion (%) 3.3 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Azithromycin | Pooled proportion (%) 1.2 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Clindamycin | Pooled proportion (%) 3.0 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin 2000 mg | Pooled proportion (%) 22.4 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin + clavulanic acid | Pooled proportion (%) 34.7 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 7 days | Pooled proportion (%) 38.2 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 1 day | Pooled proportion (%) 1.7 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 9 days | (3 mentions) GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic regimens by grouped category Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Extended (>=8 days) | Pooled proportion (%) 6.3 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin-clavulanic acid dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin-clavulanic acid 875/125 mg | Pooled proportion (%) 53 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin-clavulanic acid dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin-clavulanic acid 875 mg | Pooled proportion (%) 4.7 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic regimens by grouped category Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Long (6-7 days) | Pooled proportion (%) 44.2 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 8 days | Pooled proportion (%) 3.3 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 5 days | Pooled proportion (%) 33.4 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Clarithromycin | Pooled proportion (%) 0.4 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Timing of pre-operative antibiotic administration Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 1 hour or immediately prior | Pooled proportion (%) 47.4 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Timing of pre-operative antibiotic administration Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 1 or 2 days prior | Pooled proportion (%) 51.6 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin-clavulanic acid dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin-clavulanic acid 625 mg | Pooled proportion (%) 16.3 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin-clavulanic acid dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin-clavulanic acid 500/125 mg | Pooled proportion (%) 11.5 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin-clavulanic acid dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin-clavulanic acid 1000 mg | Pooled proportion (%) 6.8 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Distribution of antibiotics reported (percent of all mentioned antibiotics) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin | Pooled proportion (%) 50.9 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin 750 mg | Pooled proportion (%) 17 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin 500 mg | Pooled proportion (%) 37.3 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Duration of post-operative antibiotic course by number of days (percent of mentions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · 6 days | Pooled proportion (%) 6.0 GRADE not reported Studies not reported |
| Dentist survey respondents reporting antibiotic regimens for dental implant surgery | Antibiotic regimen used for dental implant surgery | None | Amoxicillin dose distribution (within-antibiotic share of prescriptions) Global (dentist surveys, patient records and registers; mostly Europe and high-income settings) · Amoxicillin 1000 mg | Pooled proportion (%) 15.5 GRADE not reported Studies not reported |
Included primary studies 38
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| A Baudet et al. 2020 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| AbuKaraky et al. 2011 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Al Marah et al. 2022 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Al-Kattan & Al-Shibani 2018 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Alamri et al. 2025 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| AlSarhan 2020 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Aragoneses et al. 2020 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Arteagoitia et al. 2018 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Bazsefidpay et al. 2023 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Becker et al. 2024 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Becker et al. 2024 Opiate receptors in the central nervous system. PMID:202433 | 1977 | this review only | not stated | not extracted yet |
| Bianco et al. 2021 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Camacho-Alonso et al. 2019 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Camps-Font 2018 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Chehabeddine et al. 2022 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Correia et al. 2024 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Datta et al. 2014 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Deeb et al. 2015 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Dominiak et al. 2020 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| El-Kholey et al. 2018 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Farkaš et al. 2021 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Froum & Weinberg 2015 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| George et al. 2022 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Hubbard et al. 2022 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Ireland et al. 2019 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Khalil et al. 2015 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Köhler et al. 2013 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Ković et al. 2025 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Loume et al. 2023 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Momand et al. 2025 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Peter et al. 2024 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Salgado-Peralvo et al. 2021 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Sánchez et al. 2019A matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Sbricoli et al. 2024 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Suda et al. 2019 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Torof et al. 2024 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Williams 2020 matched by author and year (probable) | NR | this review only | Prevalence of dentist-reported routine antibiotic prescribing | not extracted yet |
| Yalcin-Ülker et al. 2020 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Dentists who perform dental implant surgery, or patients undergoing dental implant surgery | Dentists (n=7266; 32 survey studies plus 1 combined) and patients (n=137,207; 4 patient-record cohorts, 2 registry studies, 1 combined) |
| Intervention | Antibiotic prescribing practice in relation to dental implant surgery | Antibiotic prescribing for dental implant surgery |
| Comparison | Not applicable | Not applicable |
| Outcomes | Prevalence of prophylaxis use; prescription appropriateness; factors associated with prescribing; drug type, dose, route and timing | Pooled prevalence of routine antibiotic prescribing 61.3% (24 reports); timing, complexity, procedure and risk-factor subgroups; regimens; guideline adherence (narrative) |
| Study designs | Cross-sectional studies, surveys of dentists, clinical record audits, registry studies, cohort or case-control studies | Dentist surveys (n=32), patient-record cohorts (n=4), registry studies (n=2), survey plus patient record (n=1) |
| Timing | Not specified | Studies published 2010-2025 |