Non-Cochrane · intervention · PM42251737
Effect of Fluorescent Adhesives on Visibility and Tooth Enamel Surface Properties After Debonding: A Systematic Review and Meta-Analysis.
Omidkhoda Maryam, Bardideh Erfan, Nowabadi Alireza, et al. · Clinical and experimental dental research · 2026 · PubMed · doi:10.1002/cre2.70385
Findings
Population Extracted human or bovine teeth undergoing orthodontic bracket bonding and debonding (in vitro)
7 findings
| Fluorescent orthodontic adhesives | Conventional non-fluorescent adhesives | Shear bond strength (MPa) After debonding · Laboratory · Human teeth only (bovine sample excluded) | MD 2.64 [-1.54, 6.82] GRADE not reported 4 studies · 180 participants |
| Fluorescent orthodontic adhesives | Conventional non-fluorescent adhesives | Enamel damage index (EDI) After debonding · Laboratory | MD -0.04 [-0.28, 0.2] Very low Downgraded: risk of bias, imprecision, indirectness 3 studies · 108 participants |
| Fluorescent orthodontic adhesives | Conventional non-fluorescent adhesives | Adhesive remnant index (ARI) After debonding · Laboratory | MD 0.18 [-0.1, 0.46] Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness 6 studies · 270 participants |
| Fluorescent orthodontic adhesives | Conventional non-fluorescent adhesives | Residual adhesive surface area (mm2) After debonding · Laboratory | MD -0.57 [-1.13, -0.02] Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness 5 studies · 326 participants |
| Fluorescent orthodontic adhesives | Conventional non-fluorescent adhesives | Adhesive remnant index (ARI) After debonding · Laboratory · Human teeth only (bovine sample excluded) | MD 0.29 [0.04, 0.55] GRADE not reported 5 studies · 238 participants |
| Fluorescent orthodontic adhesives | Conventional non-fluorescent adhesives | Adhesive removal time (s) After debonding · Laboratory | MD -24.89 [-50.29, 0.51] Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness 6 studies · 348 participants |
| Fluorescent orthodontic adhesives | Conventional non-fluorescent adhesives | Shear bond strength (MPa) After debonding · Laboratory | MD 1.07 [-3.05, 5.19] Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness 5 studies · 212 participants |
Included primary studies 19
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Albertini 2022 Fluorescence-aided removal of orthodontic composites: an in vivo comparative study. PMID:35599253 | 2022 | this review only | not stated | not extracted yet |
| AlSamak 2023 Evaluation of the shear bond strength and adhesive remnant index of color change, fluorescent, and conventional orthodontic adhesives: An… PMID:36493626 | 2023 | this review only | Shear bond strength (MPa); Adhesive remnant index (ARI) | not extracted yet |
| Asokan 2024 matched by author and year (probable) | NR | this review only | Shear bond strength (MPa); Adhesive remnant index (ARI); Residual adhesive surface area (mm2); Enamel damage index (EDI); Adhesive removal time (s) | not extracted yet |
| Chung 2024 Optimizing Ultraviolet Illumination for Detecting Fluorescent Orthodontic Adhesive Residues during Debonding Procedures. PMID:38930329 | 2024 | this review only | not stated | not extracted yet |
| Engeler 2021 Fluorescence-Aided Identification Technique (FIT) Improves Tooth Surface Clean-Up after Debonding of Buccal and Lingual Orthodontic… PMID:35011955 | 2021 | this review only | Residual adhesive surface area (mm2) | not extracted yet |
| Farronato 2021 Evaluation of Dental Surface after De-Bonding Orthodontic Bracket Bonded with a Novel Fluorescent Composite: In Vitro Comparative Study DOI:10.3390/app11146354 | 2021 | this review only | Adhesive remnant index (ARI); Adhesive removal time (s) | not extracted yet |
| Kaneshima 2018 Using UV light for adhesive remnant removal after debonding of orthodontic accessories. PMID:30281682 | 2018 | this review only | not stated | not extracted yet |
| Kim 2018 Detection of residual resin-based orthodontic adhesive based on light-induced fluorescence. PMID:30179668 | 2018 | this review only | not stated | not extracted yet |
| Lai 2019 An in vitro comparison of ultraviolet versus white light in the detection of adhesive remnants during orthodontic debonding. PMID:30653333 | 2019 | this review only | Residual adhesive surface area (mm2); Adhesive removal time (s) | not extracted yet |
| Moecke 2022 Efficacy of Bracket Adhesive Remnant Removal by a Fluorescence-Aided Identification Technique with a UV Light Handpiece: In Vitro Study. PMID:36249726 | 2022 | this review only | Adhesive removal time (s) | not extracted yet |
| Namura 2010 Usefulness of orthodontic adhesive-containing fluorescent dye. PMID:20466771 | 2010 | this review only | Shear bond strength (MPa); Adhesive remnant index (ARI) | not extracted yet |
| Ribeiro 2017 Assessing adhesive remnant removal and enamel damage with ultraviolet light: An in-vitro study. PMID:28153158 | 2017 | this review only | Enamel damage index (EDI) | not extracted yet |
| Rocha 2017 Efficacy of auxiliary devices for removal of fluorescent residue after bracket debonding. PMID:28035838 | 2017 | this review only | not stated | not extracted yet |
| Rossato 2020 Do fluorescent agents alter the mechanical strength of orthodontic adhesives? An in vitro and clinical study. PMID:32037477 | 2020 | this review only | Shear bond strength (MPa); Adhesive remnant index (ARI) | not extracted yet |
| Schott 2018 A new Fluorescence-aided Identification Technique (FIT) for optimal removal of resin-based bracket bonding remnants after orthodontic… PMID:30264058 | 2018 | this review only | not stated | not extracted yet |
| Stadler 2019 Evaluation of a Fluorescence-aided Identification Technique (FIT) to assist clean-up after orthodontic bracket debonding. PMID:31206307 | 2019 | this review only | Residual adhesive surface area (mm2); Adhesive removal time (s) | not extracted yet |
| Wu 2023 Quantitative light-induced fluorescence enables effective detection of orthodontic adhesive residues in diverse environments. PMID:37567330 | 2023 | this review only | not stated | not extracted yet |
| Yamagata 2018 DOI:10.11344/nano.10.53 | NR | this review only | not stated | not extracted yet |
| Yan 2024 In vitro evaluation of an easy-to-remove orthodontic adhesive with photochromic property. PMID:38052230 | 2024 | this review only | Shear bond strength (MPa); Adhesive remnant index (ARI); Residual adhesive surface area (mm2); Enamel damage index (EDI); Adhesive removal time (s) | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Teeth subjected to orthodontic bonding (in vitro or in vivo) | Extracted human and bovine teeth and brackets; 17 in vitro and 2 in vivo studies (n=19); 11 in vitro studies in meta-analysis |
| Intervention | Orthodontic adhesives containing fluorescent materials | Fluorescent adhesives with UV, FIT or conventional illumination (n=19) |
| Comparison | Conventional adhesives without fluorescent materials | Conventional adhesives such as Transbond XT (n=19) |
| Outcomes | Enamel loss, shear bond strength, adhesive remnant index, surface roughness, residual adhesive surface area, adhesive removal time | SBS (n=5), ARI (n=6), residual adhesive area (n=5), EDI (n=3), removal time (n=6) |
| Study designs | Laboratory and clinical studies reporting quantitative data on at least one outcome | In vitro studies (n=17) and in vivo studies (n=2); one study with in vitro and clinical phases |
| Timing | Not specified | After debonding |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | Partial Yes | Partial Yes | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | Partial Yes | Partial Yes | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | Yes | Yes | yes |
| 7List of excluded studies with reasonscritical | No | No | yes |
| 8Included studies described in detail | Partial Yes | Partial Yes | yes |
| 9Risk of bias assessed satisfactorilycritical | RCT: Yes · NRSI: Yes | NRSI: Yes · RCT: Yes | no |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: Yes · NRSI: N/A | NRSI: Yes · RCT: Yes | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | Yes | Yes | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | No | No | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Critically Low | Critically Low | yes |