Non-Cochrane · intervention · PM42244488
Infectious complications of dental procedures in dogs and cats, and the impact of antimicrobial prophylaxis: a systematic review.
Weese J S, Soltero-Rivera M, Weese H E, et al. · The Journal of small animal practice · 2026 · PubMed · doi:10.1111/jsap.70147
Findings
Population Dogs and cats undergoing dental procedures
7 findings
| Dental procedure (scaling, root planing, extractions) | None (prevalence) | Bacteraemia (any timepoint) Species: canine | Prevalence 0.48 [0.23, 0.74] GRADE not reported 6 studies · 139 participants |
| Dental procedures (scaling, root planing, extractions) | None (single-group prevalence) | Bacteraemia after dental procedures (pooled prevalence) Any timepoint (overall prevalence; otherwise timepoint with highest prevalence) · All studies, as stated in Abstract and Results text | Pooled prevalence 0.47 [0.26, 0.68] GRADE not reported 7 studies · 150 participants |
| Dental procedure (scaling, root planing, extractions) | None (prevalence) | Incidence of sepsis or infective endocarditis | No studies clearly reported sepsis or infective endocarditis data No studies found 0 studies |
| Dental procedure (scaling, root planing, extractions) | None (prevalence) | Bacteraemia (any timepoint) | Prevalence 0.47 [0.26, 0.68] GRADE not reported 7 studies · 150 participants |
| Peri-procedural antimicrobials (penicillin, clindamycin) | No antimicrobials (untreated control) | Bacteraemia After procedure (any timepoint) | RR 1.09 [0.70, 1.67] 47 [-156, 348] per 1000 Very low Downgraded: risk of bias, imprecision, indirectness 2 studies · 55 participants |
| Peri-procedural antimicrobial prophylaxis | No antimicrobial prophylaxis | Endocarditis, sepsis or other infectious complications | No studies that evaluated the impact on endocarditis, sepsis or other infectious complications were identified. No studies found 0 studies |
| Post-procedural antimicrobials | No post-procedural antimicrobials | Endocarditis, sepsis, bacteraemia or other infectious complications | No data were available to assess this question No studies found 0 studies |
Included primary studies 12
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Black 1980 matched by author and year (probable) | NR | this review only | Bacteraemia (any timepoint); Bacteraemia | not extracted yet |
| Blazevich 2024 The Presence of Bacteremia in 13 Dogs Undergoing Oral Surgery Without the Use of Antibiotic Therapy. PMID:37997386 | 2024 | this review only | Bacteraemia (any timepoint) | not extracted yet |
| Bowersock 2000 Prevention of bacteremia in dogs undergoing dental scaling by prior administration of oral clindamycin or chlorhexidine oral rinse. PMID:11968927 | 2000 | this review only | Bacteraemia (any timepoint); Bacteraemia | not extracted yet |
| Harari 1991 matched by author and year (probable) | NR | this review only | Bacteraemia (any timepoint) | not extracted yet |
| Harari 1993 Bacterial isolates from blood cultures of dogs undergoing dentistry. PMID:8488671 | 1993 | this review only | Bacteraemia (any timepoint) | not extracted yet |
| Lobetti 2007 Anaerobic bacterial pericardial effusion in a cat. PMID:18237044 | 2007 | this review only | not stated | not extracted yet |
| Nieves 1997 Bacterial isolates from plaque and from blood during and after routine dental procedures in dogs. PMID:9123810 | 1997 | this review only | Bacteraemia (any timepoint) | not extracted yet |
| Peddle 2009 Association of periodontal disease, oral procedures, and other clinical findings with bacterial endocarditis in dogs. PMID:19119972 | 2009 | this review only | not stated | not extracted yet |
| Ramos 2011 matched by author and year (probable) | NR | this review only | Bacteraemia (any timepoint) | not extracted yet |
| Rodriguez 1993 Salmonella choleraesuis pneumonia in a cat without signs of gastrointestinal tract disease. PMID:8468222 | 1993 | this review only | not stated | not extracted yet |
| Tou 2005 Mitral valve endocarditis after dental prophylaxis in a dog. PMID:15822575 | 2005 | this review only | not stated | not extracted yet |
| Westermeyer 2013 Actinomyces endogenous endophthalmitis in a cat following multiple dental extractions. PMID:23281798 | 2013 | this review only | not stated | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Dogs and cats undergoing dental procedures (naturally occurring disease) | Dogs and cats undergoing dental procedures (mainly dogs; 1 feline study in the pooled prevalence) |
| Intervention | Dental procedures (CoCoPop/PECO); peri-procedural or post-procedural antimicrobial administration (PICO) | Scaling, root planing, extractions; clindamycin or penicillin prophylaxis (2 RCTs) |
| Comparison | No antimicrobials or controls (PICO/PECO); none for prevalence | Untreated controls (RCTs) |
| Outcomes | Bacteraemia, sepsis, infective endocarditis, other infectious sequelae, local infection, adverse effects | Bacteraemia (7 studies, n=150 pooled prevalence); no sepsis, endocarditis or other infectious complication outcomes |
| Study designs | RCTs, cohort, case-control, cross-sectional, case series (10 or more animals), case reports (Review 1 background), conference abstracts | 2 RCTs, 5 cross-sectional studies, 1 case-control study, 4 case reports |
| Timing | Not specified | Immediately after procedure up to 1 hour |