Non-Cochrane · intervention · PM42207302
Microvascular decompression for trigeminal neuralgia secondary to vertebrobasilar dolichoectasia: a systematic review and meta-analysis.
Hajikarimloo Bardia, Mohammadzadeh Ibrahim, Tos Salem M, et al. · Acta neurochirurgica · 2026 · PubMed · doi:10.1007/s00701-026-06925-0
Findings
219 findings
| Population | ||||
|---|---|---|---|---|
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0006 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: Mean.Duration.Pain | Meta-regression coefficient (logit proportion per unit of moderator) -0.0095 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Common-effect model | Pooled proportion (%) 26 [21, 32] GRADE not reported 13 studies · 315 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Random-effects model (Hartung-Knapp) | Pooled proportion (%) 99.9 [98.7, 100] GRADE not reported 13 studies · 315 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.1430 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia secondary to vertebrobasilar dolichoectasia (VBD) or ectasia | Microvascular decompression (interposition or transposition techniques) | No comparator (single-arm proportions) | Transient complications perioperative and postoperative · Surgical (neurosurgery) centers | Pooled proportion (%) 16.7 [5.1, 32.0] GRADE not reported 12 studies · 254 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v1_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0006 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: Mean.Duration.Pain | Meta-regression coefficient (logit proportion per unit of moderator) 0.0046 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.1104 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: retrosigmoid_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0100 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0127 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0464 GRADE not reported 8 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0076 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0209 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: otherapproach_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0079 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0017 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Common-effect model | Pooled proportion (%) 5 [3, 9] GRADE not reported 13 studies · 304 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: retrosigmoid_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0098 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Common-effect model | Pooled proportion (%) 100 [99, 100] GRADE not reported 13 studies · 315 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) 0.0424 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: otherapproach_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0100 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0002 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0359 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0013 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0171 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Random-effects model (Hartung-Knapp) | Pooled proportion (%) 1.3 [0, 5] GRADE not reported 10 studies · 144 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0022 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Random-effects model (Hartung-Knapp) | Pooled proportion (%) 5.5 [2.7, 8.9] GRADE not reported 13 studies · 304 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0277 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0251 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0203 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0072 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Abstract-reported estimate (model not stated) | Pooled proportion (%) 5.5 [2.9, 8.9] GRADE not reported 13 studies · 304 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0169 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0017 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0104 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: Mean.Duration.Pain | Meta-regression coefficient (logit proportion per unit of moderator) -0.0169 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0170 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) 0.0788 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0182 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0548 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0354 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0036 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: v1_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0325 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0195 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: v1_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0335 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Abstract-reported estimate (model not stated) | Pooled proportion (%) 2.4 [0.8, 4.8] GRADE not reported 12 studies · 254 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: otherapproach_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0098 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) 0.0042 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: otherapproach_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0086 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: Mean.Duration.Pain | Meta-regression coefficient (logit proportion per unit of moderator) -0.0023 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0183 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0359 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: v1_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0099 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) 0.0013 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0850 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0139 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: otherapproach_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0049 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0170 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0351 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) 0.0146 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0029 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) 0.0106 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: retrosigmoid_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0008 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0277 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0017 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0206 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) -0.0092 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0169 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0107 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0177 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Abstract-reported estimate (model not stated) | Pooled proportion (%) 92.6 [88.4, 96.1] GRADE not reported 10 studies · 232 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) 0.0007 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0071 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0141 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0113 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0229 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0310 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0089 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0020 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0344 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0124 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: otherapproach_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0138 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0073 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) 0.0275 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia secondary to vertebrobasilar dolichoectasia (VBD) or ectasia | Microvascular decompression (interposition or transposition techniques) | No comparator (single-arm proportions) | Pain recurrence follow-up (mean 14.0 to 118.8 months) · Surgical (neurosurgery) centers · Sensitivity: trim-and-fill (4 imputed studies) | Pooled proportion (%), trim-and-fill adjusted random effects 7.7 [3.1, 13.6] GRADE not reported 17 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0172 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0242 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0096 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0104 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0050 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0126 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0378 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0002 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Random-effects model (Hartung-Knapp) | Pooled proportion (%) 24.3 [12.7, 37.8] GRADE not reported 13 studies · 315 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0051 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0076 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: v1_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0536 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0341 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0079 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: v1_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0011 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0040 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Random-effects model (Hartung-Knapp) | Pooled proportion (%) 92.6 [83.9, 98.5] GRADE not reported 10 studies · 232 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0576 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0052 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) -0.0098 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: otherapproach_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0043 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0071 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0006 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: retrosigmoid_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0086 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0120 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0170 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0029 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0033 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0146 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0029 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0050 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia secondary to vertebrobasilar dolichoectasia (VBD) or ectasia | Microvascular decompression (interposition or transposition techniques) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) last follow-up (mean 14.0 to 118.8 months) · Surgical (neurosurgery) centers · Sensitivity: trim-and-fill (5 imputed studies) | Pooled proportion (%), trim-and-fill adjusted random effects 92.8 [86.7, 97.5] GRADE not reported 17 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0575 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0007 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0197 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: retrosigmoid_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0079 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: otherapproach_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0008 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0046 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0015 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0040 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0389 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0555 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0072 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0046 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: Mean.Duration.Pain | Meta-regression coefficient (logit proportion per unit of moderator) 0.0073 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0124 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Abstract-reported estimate (model not stated) | Pooled proportion (%) 95.8 [92.3, 98.2] GRADE not reported 13 studies · 315 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0047 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0203 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0290 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0033 GRADE not reported 8 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Common-effect model | Pooled proportion (%) 18 [13, 23] GRADE not reported 12 studies · 254 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) 0.0000 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0040 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0144 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0087 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) 0.0016 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0045 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0043 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0001 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0378 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) 0.1189 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0001 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0411 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0602 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.1367 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Common-effect model | Pooled proportion (%) 2 [0, 5] GRADE not reported 12 studies · 254 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: retrosigmoid_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0138 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Random-effects model (Hartung-Knapp) | Pooled proportion (%) 95.9 [92.4, 98.5] GRADE not reported 12 studies · 250 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) 0.0956 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) -0.0035 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: Mean.Duration.Pain | Meta-regression coefficient (logit proportion per unit of moderator) 0.0067 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0258 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Common-effect model | Pooled proportion (%) 96 [92, 98] GRADE not reported 13 studies · 315 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0130 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0926 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Abstract-reported estimate (model not stated) | Pooled proportion (%) 1.3 [0.2, 3.1] GRADE not reported 10 studies · 144 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: retrosigmoid_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0049 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0055 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0210 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0025 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: Mean.Follow.Up | Meta-regression coefficient (logit proportion per unit of moderator) 0.0105 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0110 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0205 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0220 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0022 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0141 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0304 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: retrosigmoid_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0043 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v1_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0209 GRADE not reported 8 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.1300 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) 0.0242 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0311 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0235 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Common-effect model | Pooled proportion (%) 1 [0, 5] GRADE not reported 10 studies · 144 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0167 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0023 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0127 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Abstract-reported estimate (model not stated) | Pooled proportion (%) 99.9 [98.2, 100] GRADE not reported 13 studies · 315 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0619 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: transposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0082 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0086 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0202 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: interposition_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0078 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: prior_rhizotomy_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0159 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0172 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia secondary to vertebrobasilar dolichoectasia (VBD) or ectasia | Microvascular decompression (interposition or transposition techniques) | No comparator (single-arm proportions) | Permanent complications perioperative and postoperative · Surgical (neurosurgery) centers | Pooled proportion (%) 2.4 [0.4, 5.4] GRADE not reported 12 studies · 254 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0538 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Transient complications Resolved during follow-up · Univariate meta-regression moderator: ba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0169 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: va_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0076 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0089 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Abstract-reported estimate (model not stated) | Pooled proportion (%) 95.9 [91.8, 98.8] GRADE not reported 12 studies · 250 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0329 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0191 GRADE not reported 9 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: Mean.Duration.Pain | Meta-regression coefficient (logit proportion per unit of moderator) -0.0009 GRADE not reported 8 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: v1v2_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0079 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: prior_srs_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0236 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0073 GRADE not reported 13 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: v1v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0351 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Pain recurrence Follow-up after initial response · Univariate meta-regression moderator: v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0027 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: female_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0172 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial adequate pain relief (BNI I-IIIb) First follow-up after MVD · Univariate meta-regression moderator: v2v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0113 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: right_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0359 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: Mean.Age | Meta-regression coefficient (logit proportion per unit of moderator) -0.0135 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Univariate meta-regression moderator: v3_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0190 GRADE not reported 11 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Permanent complications Lasting deficits at follow-up · Univariate meta-regression moderator: vaba_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0072 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Univariate meta-regression moderator: left_percentage | Meta-regression coefficient (logit proportion per unit of moderator) -0.0096 GRADE not reported 12 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up complete pain relief (BNI I) Last follow-up (mean 14.0 to 118.8 months) · Common-effect model | Pooled proportion (%) 90 [86, 94] GRADE not reported 10 studies · 232 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: male_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0341 GRADE not reported 10 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Salvage intervention Follow-up after recurrence · Univariate meta-regression moderator: Mean.Duration.Pain | Meta-regression coefficient (logit proportion per unit of moderator) 0.0236 GRADE not reported 8 studies |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Initial complete pain relief (BNI I) First follow-up after MVD · Random-effects model (Hartung-Knapp) | Pooled proportion (%) 95.8 [90.5, 99.3] GRADE not reported 13 studies · 315 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Last follow-up adequate pain relief (BNI I-IIIb) Last follow-up (mean 14.0 to 118.8 months) · Common-effect model | Pooled proportion (%) 96 [92, 98] GRADE not reported 12 studies · 250 participants |
| Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia (VBD-TN) | Microvascular decompression (interposition or transposition) | No comparator (single-arm proportions) | Overall complications Perioperative and postoperative · Univariate meta-regression moderator: v1_percentage | Meta-regression coefficient (logit proportion per unit of moderator) 0.0489 GRADE not reported 11 studies |
Included primary studies 24
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| El-Ghandour 2010 Microvascular Decompression in the Treatment of Trigeminal Neuralgia Caused by Vertebrobasilar Ectasia DOI:10.1227/01.neu.0000371978.86528.60 | 2010 | this review only | not stated | not extracted yet |
| El-Ghandour 2010 Microvascular decompression in the treatment of trigeminal neuralgia caused by vertebrobasilar ectasia. PMID:20644418 | 2010 | this review only | not stated | not extracted yet |
| Gao 2025 Efficacy analysis of microvascular decompression and percutaneous balloon compression for trigeminal neuralgia secondary to… DOI:10.1007/s00701-025-06651-z | 2025 | this review only | not stated | not extracted yet |
| Gao 2025 Efficacy analysis of microvascular decompression and percutaneous balloon compression for trigeminal neuralgia secondary to… PMID:40836140 | 2025 | this review only | not stated | not extracted yet |
| Honey 2018 Trigeminal Neuralgia due to Vertebrobasilar Artery Compression DOI:10.1016/j.wneu.2018.06.145 | 2018 | this review only | not stated | not extracted yet |
| Honey 2018 Trigeminal Neuralgia due to Vertebrobasilar Artery Compression. PMID:29959080 | 2018 | this review only | not stated | not extracted yet |
| Ma 2013 Clinical analysis of trigeminal neuralgia caused by vertebrobasilar dolichoectasia DOI:10.1007/s10143-013-0468-8 | 2013 | this review only | not stated | not extracted yet |
| Ma 2013 Clinical analysis of trigeminal neuralgia caused by vertebrobasilar dolichoectasia. PMID:23645139 | 2013 | this review only | not stated | not extracted yet |
| Ruiz-Juretschke 2016 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Shulev 2020 Microvascular decompression in trigeminal neuralgia following vertebrobasilar dolichoectasia DOI:10.17116/neiro20208405150 | 2020 | this review only | not stated | not extracted yet |
| Shulev 2020 [Microvascular decompression in trigeminal neuralgia following vertebrobasilar dolichoectasia]. PMID:33095533 | 2020 | this review only | not stated | not extracted yet |
| Sun 2017 Clinical analysis and surgical treatment of trigeminal neuralgia caused by vertebrobasilar dolichoectasia: A retrospective study DOI:10.1016/j.ijsu.2017.04.015 | 2017 | this review only | not stated | not extracted yet |
| Sun 2017 Clinical analysis and surgical treatment of trigeminal neuralgia caused by vertebrobasilar dolichoectasia: A retrospective study. PMID:28392449 | 2017 | this review only | not stated | not extracted yet |
| Sun 2024 Fully Endoscopic Microvascular Decompression for Trigeminal Neuralgia Caused by Vertebrobasilar Artery: A Case Series Review:… DOI:10.1227/ons.0000000000000998 | 2023 | this review only | not stated | not extracted yet |
| Sun 2024 Fully Endoscopic Microvascular Decompression for Trigeminal Neuralgia Caused by Vertebrobasilar Artery: A Case Series Review:… PMID:37976445 | 2024 | this review only | not stated | not extracted yet |
| Vanaclocha 2016 Is There a Safe and Effective Way to Treat Trigeminal Neuralgia Associated with Vertebrobasilar Dolichoectasia? Presentation of 8 Cases… DOI:10.1016/j.wneu.2016.08.085 | 2016 | this review only | not stated | not extracted yet |
| Vanaclocha 2016 Is There a Safe and Effective Way to Treat Trigeminal Neuralgia Associated with Vertebrobasilar Dolichoectasia? Presentation of 8 Cases… PMID:27586175 | 2016 | this review only | not stated | not extracted yet |
| Yang 2012 Microvascular decompression on patients with trigeminal neuralgia caused by ectatic vertebrobasilar artery complex: technique notes DOI:10.1007/s00701-012-1320-6 | 2012 | this review only | not stated | not extracted yet |
| Yang 2012 Microvascular decompression on patients with trigeminal neuralgia caused by ectatic vertebrobasilar artery complex: technique notes. PMID:22441581 | 2012 | this review only | not stated | not extracted yet |
| Yu 2022 Microvascular decompression by interposition method for treatment of trigeminal neuralgia due to vertebrobasilar dolichoectasia: a… DOI:10.1007/s10143-022-01776-6 | 2022 | this review only | not stated | not extracted yet |
| Yu 2022 Microvascular decompression by interposition method for treatment of trigeminal neuralgia due to vertebrobasilar dolichoectasia: a… PMID:35391607 | 2022 | this review only | not stated | not extracted yet |
| Zhao 2021 Comparison of Microvascular Decompression and Two Isocenters Gamma Knife for the Treatment of Trigeminal Neuralgia Caused by… PMID:34526959 | 2021 | this review only | not stated | not extracted yet |
| Zheng 2023 Trigeminal neuralgia caused by vertebrobasilar dolichoectasia: efficacy of stepwise decompression technique DOI:10.1007/s00701-023-05691-7 | 2023 | this review only | not stated | not extracted yet |
| Zheng 2023 Trigeminal neuralgia caused by vertebrobasilar dolichoectasia: efficacy of stepwise decompression technique. PMID:37353618 | 2023 | this review only | not stated | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Patients with trigeminal neuralgia caused by vertebrobasilar dolichoectasia/ectasia confirmed by imaging and/or intraoperative findings; at least 7 VBD patients undergoing MVD | VBD-TN patients who had MVD (n=315) |
| Intervention | Microvascular decompression (interposition, sling or transposition techniques) | MVD; interposition 79.1% and transposition 20.9% among 254 with detailed techniques |
| Comparison | No comparator required; alternative treatments (radiosurgery, percutaneous procedures, medical therapy) if available | No comparator (single-arm proportions) |
| Outcomes | Barrow Neurological Institute pain scores (complete BNI I, adequate BNI I-IIIb), recurrence, salvage interventions, complications (transient, permanent) | Initial and last follow-up complete and adequate pain relief, pain recurrence, salvage intervention, overall, transient and permanent complications |
| Study designs | Prospective or retrospective cohort studies and case series; full text in English | 13 non-randomized studies (retrospective cohorts and case series), 2010 to 2025 |
| Timing | Initial and last follow-up | Mean follow-up 14.0 to 118.8 months |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | No | No | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | No | No | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | Yes | Yes | yes |
| 7List of excluded studies with reasonscritical | Partial Yes | Partial Yes | yes |
| 8Included studies described in detail | Partial Yes | Partial Yes | yes |
| 9Risk of bias assessed satisfactorilycritical | RCT: N/A · NRSI: Partial Yes | NRSI: Partial Yes · RCT: N/A | no |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: N/A · NRSI: Yes | NRSI: Yes · RCT: N/A | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | Yes | Yes | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | Yes | Yes | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Critically Low | Critically Low | yes |