Non-Cochrane · prognostic · PM42205315
Efficacy of narrow-diameter implants in restoring dentition defects in patients with diabetes: A systematic review and meta-analysis.
Zhang Zhihong, Wang Ding, Li Jun · Biomedical reports · 2026 · PubMed · doi:10.3892/br.2026.2156
Findings
17 findings
| Population | ||||
|---|---|---|---|---|
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Plaque index <=1 year · Dental implant clinics (outpatient) · Follow-up <=1 year | MD 9.97 [-13.72, 33.65] GRADE not reported 2 studies · 107 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Bleeding on probing <=1 year · Dental implant clinics (outpatient) · Follow-up <=1 year | MD 10.40 [-16.77, 37.57] GRADE not reported 2 studies · 107 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter 3.5 mm or less) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Distal crestal bone loss Longest available follow-up | MD 0.28 [0.02, 0.53] GRADE not reported 4 studies · 217 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Probing depth All follow-up · Dental implant clinics (outpatient) · Overall | MD 0.23 [0.15, 0.31] GRADE not reported 8 studies · 643 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter 3.5 mm or less) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Mesial crestal bone loss Longest available follow-up | MD 0.31 [-0.04, 0.66] GRADE not reported 4 studies · 217 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Plaque index 1-3 years · Dental implant clinics (outpatient) · Follow-up 1-3 years | MD 10.44 [-12.22, 33.09] GRADE not reported 2 studies · 125 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Probing depth <=1 year · Dental implant clinics (outpatient) · Follow-up <=1 year | MD 0.26 [0.18, 0.34] GRADE not reported 3 studies · 165 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Plaque index >=3 years · Dental implant clinics (outpatient) · Follow-up >=3 years | MD 13.77 [0.54, 26.99] GRADE not reported 5 studies · 298 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Probing depth >=3 years · Dental implant clinics (outpatient) · Follow-up >=3 years | MD 0.31 [0.16, 0.46] GRADE not reported 6 studies · 327 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Bleeding on probing >=3 years · Dental implant clinics (outpatient) · Follow-up >=3 years | MD 14.41 [2.37, 26.46] GRADE not reported 4 studies · 248 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Bleeding on probing 1-3 years · Dental implant clinics (outpatient) · Follow-up 1-3 years | MD 12.55 [-9.86, 34.96] GRADE not reported 2 studies · 125 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter 3.5 mm or less) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Plaque index All follow-up times pooled | MD 12.15 [3.78, 20.52] GRADE not reported 7 studies · 530 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Implant survival rate Mixed follow-up (6 months to 4 years) · Dental implant clinics (outpatient) · Overall | RR 1.00 [0.93, 1.07] GRADE not reported 4 studies · 112 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter 3.5 mm or less) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Bleeding on probing All follow-up times pooled | MD 13.06 [4.58, 21.54] GRADE not reported 6 studies · 480 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Marginal bone loss Longest follow-up · Dental implant clinics (outpatient) · Overall | MD -0.02 [-0.21, 0.17] GRADE not reported 4 studies · 158 participants |
| Adults with type 2 diabetes receiving narrow-diameter implants (diameter <=3.5 mm) for tooth replacement | Narrow-diameter implants in patients with diabetes | Narrow-diameter implants in patients without diabetes | Probing depth 1-3 years · Dental implant clinics (outpatient) · Follow-up 1-3 years | MD 0.11 [-0.12, 0.34] GRADE not reported 3 studies · 151 participants |
| Adults with type 1 or type 2 diabetes receiving narrow-diameter implants | Narrow-diameter implants in patients with diabetes and HbA1c <=7% | Narrow-diameter implants in patients with diabetes and HbA1c >7% | Implant and peri-implant outcomes | Subgroup analyses based on glycemic control (HbA1c <=7 vs >7%) could not be performed due to insufficient data in the included studies. No studies found 0 studies · 0 participants |
Included primary studies 9
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Al-Shibani 2019 Comparison of clinical peri-implant indices and crestal bone levels around narrow and regular diameter implants placed in diabetic and… PMID:30624014 | 2019 | this review only | not stated | not extracted yet |
| Alsahhaf 2019 Clinical and radiographic indices around narrow diameter implants placed in different glycemic-level patients. PMID:31037825 | 2019 | this review only | not stated | not extracted yet |
| Alsahhaf 2022 Clinical, Radiographic, and Inflammatory Peri-Implant Parameters around Narrow Diameter Implant Crowns among Prediabetic and Non-Diabetic… PMID:36557041 | 2022 | this review only | not stated | not extracted yet |
| Alshahrani 2020 Comparison of peri-implant soft tissue and crestal bone status of dental implants placed in prediabetic, type 2 diabetic, and non-diabetic… PMID:33015750 | 2020 | this review only | not stated | not extracted yet |
| Cabrera-Dominguez 2017 A Prospective Case-Control Clinical Study of Titanium-Zirconium Alloy Implants with a Hydrophilic Surface in Patients with Type 2 Diabetes… PMID:28906508 | 2017 | this review only | not stated | not extracted yet |
| Cabrera-Dominguez 2020 Clinical performance of titanium-zirconium implants with a hydrophilic surface in patients with controlled type 2 diabetes mellitus:… PMID:31701247 | 2020 | this review only | not stated | not extracted yet |
| Diehl 2024 Restoration of posterior teeth by narrow diameter implants in hyperglycemic and normoglycemic patients - 4-year results of a case-control… PMID:38907052 | 2024 | this review only | not stated | not extracted yet |
| Friedmann 2021 One-year performance of posterior narrow diameter implants in hyperglycemic and normo-glycemic patients-a pilot study. PMID:33939006 | 2021 | this review only | not stated | not extracted yet |
| Tulbah 2023 Clinical peri-implant outcomes, technical complications, and patient satisfaction with single vs. splinted crown supported implants in the… PMID:36876665 | 2023 | this review only | not stated | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Adults (18 years or older) with type 1 or type 2 diabetes receiving narrow-diameter implants (diameter 3.5 mm or less) for tooth replacement | Adults with type 2 diabetes (n=410 patients; 688 implants); no type 1 diabetes studies |
| Intervention | Placement of narrow-diameter implants in patients with diabetes | Narrow-diameter implants (2.9 to 3.3 mm) in patients with type 2 diabetes |
| Comparison | Narrow-diameter implants in patients without diabetes, or diabetic subgroups (HbA1c 7% or less vs above 7%) | Narrow-diameter implants in patients without diabetes (n=9 studies) |
| Outcomes | Implant survival rate; marginal bone loss and mesial/distal crestal bone loss; probing depth; bleeding on probing; plaque index | Implant survival (n=4); marginal bone loss (n=4); mesial and distal crestal bone loss (n=4); probing depth (n=8); bleeding on probing (n=6); plaque index (n=7) |
| Study designs | RCTs, cohort studies and cross-sectional studies | Seven cohort studies and two cross-sectional studies; no RCTs |
| Timing | Minimum 6 months follow-up after loading; time-stratified analysis (<=1 year, 1-3 years, >=3 years) | Follow-up from 3 months to 120 months |