Non-Cochrane · intervention · PM42104738

Systematic Review Evaluating the Influence of Veneering Design on the Clinical Outcome of All-Ceramic Implant-Supported 3-4 Units and Full Arch Fixed Dental Prostheses.

Bishti Shaza, Wolfart Stefan, Zwahlen Marcel, et al. · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026 · PubMed · doi:10.1111/jerd.70177

Findings

31 findings

Population
Partially or completely edentulous patients with posterior implant-supported 3-4 unit all-ceramic FDPsAll-ceramic implant-supported 3-4 unit FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Complications: annual complication rate
Annual · University and private clinic
Annual complication rate (%) 3.75 [1.31, 10.7]
GRADE not reported
7 studies
Partially or completely edentulous patients with posterior implant-supported 3-4 unit all-ceramic FDPsAll-ceramic implant-supported 3-4 unit FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Survival: annual failure rate
Annual (mean follow-up 2.8 years) · University and private clinic
Annual failure rate (%) 0.46 [0.24, 0.88]
GRADE not reported
9 studies · 330 restorations participants
Partially or completely edentulous patients with posterior implant-supported 3-4 unit all-ceramic FDPsAll-ceramic implant-supported 3-4 unit FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Complications: 3-year complication-free (success) rate
3 years · University and private clinic
3-year complication-free rate (%) 89.36 [72.55, 96.14]
GRADE not reported
7 studies
Partially or completely edentulous patients with posterior implant-supported 3-4 unit all-ceramic FDPsAll-ceramic implant-supported 3-4 unit FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Chipping: 3-year chipping-free rate
3 years · University and private clinic
3-year chipping-free rate (%) 93.77 [80.17, 98.14]
GRADE not reported
8 studies
Partially or completely edentulous patients with posterior implant-supported 3-4 unit all-ceramic FDPsAll-ceramic implant-supported 3-4 unit FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Survival: 3-year survival rate
3 years · University and private clinic
3-year survival rate (%) 98.64 [97.40, 99.29]
GRADE not reported
9 studies · 330 restorations participants
Partially or completely edentulous patients with posterior implant-supported 3-4 unit all-ceramic FDPsAll-ceramic implant-supported 3-4 unit FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Chipping: annual chipping rate
Annual · University and private clinic
Annual chipping rate (%) 2.15 [0.62, 7.37]
GRADE not reported
8 studies
Partially or completely edentulous patients with implant-supported full-arch all-ceramic FDPsAll-ceramic implant-supported full-arch FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Chipping: 3-year chipping-free rate
3 years · University and private clinic
3-year chipping-free rate (%) 81.23 [77.31, 84.55]
GRADE not reported
3 studies
Partially or completely edentulous patients with implant-supported full-arch all-ceramic FDPsAll-ceramic implant-supported full-arch FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Survival: 3-year survival rate
3 years · University and private clinic
3-year survival rate (%) 96.45 [88.95, 98.88]
GRADE not reported
3 studies · 210 restorations participants
Partially or completely edentulous patients with implant-supported full-arch all-ceramic FDPsAll-ceramic implant-supported full-arch FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Complications: annual complication rate
Annual · University and private clinic
Annual complication rate (%) 9.34 [6.15, 14.17]
GRADE not reported
3 studies
Partially or completely edentulous patients with implant-supported full-arch all-ceramic FDPsAll-ceramic implant-supported full-arch FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Chipping: annual chipping rate
Annual · University and private clinic
Annual chipping rate (%) 6.93 [5.59, 8.58]
GRADE not reported
3 studies
Partially or completely edentulous patients with implant-supported full-arch all-ceramic FDPsAll-ceramic implant-supported full-arch FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Complications: 3-year complication-free (success) rate
3 years · University and private clinic
3-year complication-free rate (%) 75.57 [65.37, 83.14]
GRADE not reported
3 studies
Partially or completely edentulous patients with implant-supported full-arch all-ceramic FDPsAll-ceramic implant-supported full-arch FDPs (monolithic, micro-veneered or veneered), all designs combinedNone (single-arm pooled event rates)Survival: annual failure rate
Annual (mean follow-up 2.4 years) · University and private clinic
Annual failure rate (%) 1.2 [0.37, 3.9]
GRADE not reported
3 studies · 210 restorations participants
Patients with posterior implant-supported 3-4 unit all-ceramic FDPsMonolithic (including micro-veneered) zirconia FDPsVeneered all-ceramic FDPsComplication rate
University and private clinic · 3-4 unit FDPs
Unresolved: the two extractors disagree on this row.
Statistically significant difference between monolithic and veneered restorations in terms of complication and failure rate (p < 0.05)
GRADE not reported
9 studies
Patients with posterior implant-supported 3-4 unit all-ceramic FDPsMonolithic (including micro-veneered) zirconia FDPsVeneered all-ceramic FDPsChipping incidence
University and private clinic · 3-4 unit FDPs
Monolithic and micro-veneered restorations exhibited significantly lower incidence rates for chipping (p < 0.0001)
GRADE not reported
9 studies
Patients with posterior implant-supported 3-4 unit all-ceramic FDPsMonolithic (including micro-veneered) zirconia FDPsVeneered all-ceramic FDPsFailure rate
University and private clinic · 3-4 unit FDPs
Unresolved: the two extractors disagree on this row.
Statistically significant difference between monolithic and veneered restorations in terms of complication and failure rate (p < 0.05)
GRADE not reported
9 studies
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Micro-veneered all-ceramic FDPsMonolithic all-ceramic FDPsComplications (all types combined)
University and private clinic · All restoration types (3-4 unit and full-arch)
IRR 2.3
GRADE not reported
12 studies
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Micro-veneered all-ceramic i-FDPsMonolithic all-ceramic i-FDPsChipping
1 to 5 years follow-up
Significantly higher incidence rate ratio for micro-veneered than monolithic; no chipping in monolithic studies; value not reported
GRADE not reported
Studies not reported
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Micro-veneered all-ceramic i-FDPsMonolithic all-ceramic i-FDPsAll complications
1 to 5 years follow-up
Incidence rate ratio (IRR) 2.3
GRADE not reported
Studies not reported
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Micro-veneered all-ceramic FDPsMonolithic all-ceramic FDPsChipping incidence
University and private clinic · All restoration types (3-4 unit and full-arch)
micro-veneered and fully veneered restorations again showed significantly higher incidence rate ratios compared to monolithic designs; no chipping reported in any monolithic study
GRADE not reported
12 studies
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Veneered all-ceramic i-FDPsMonolithic all-ceramic i-FDPsAll complications
1 to 5 years follow-up
Incidence rate ratio (IRR) 2.8
GRADE not reported
Studies not reported
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Veneered all-ceramic FDPsMonolithic all-ceramic FDPsChipping incidence
University and private clinic · All restoration types (3-4 unit and full-arch)
micro-veneered and fully veneered restorations again showed significantly higher incidence rate ratios compared to monolithic designs; no chipping reported in any monolithic study
GRADE not reported
12 studies
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Veneered all-ceramic i-FDPsMonolithic all-ceramic i-FDPsChipping
1 to 5 years follow-up
Significantly higher incidence rate ratio for fully veneered than monolithic; no chipping in monolithic studies; value not reported
GRADE not reported
Studies not reported
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Veneered all-ceramic FDPsMonolithic all-ceramic FDPsComplications (all types combined)
University and private clinic · All restoration types (3-4 unit and full-arch)
IRR 2.8
GRADE not reported
12 studies
Patients with implant-supported all-ceramic FDPsFull-arch i-FDPs3-4 unit i-FDPsComplications and failure (any veneering design)
1 to 5 years follow-up
Unresolved: the two extractors disagree on this row.
Statistically significant difference between 3-4 unit FDPs and full-arch restorations (p < 0.001); no effect size reported
GRADE not reported
Studies not reported
Patients with implant-supported all-ceramic FDPs (3-4 unit and full-arch combined)Screw-retained restorationsCement-retained restorationsComplication or failure rates
University and private clinic · All restoration types (3-4 unit and full-arch)
IRR 1.15
GRADE not reported
12 studies
Patients with implant-supported all-ceramic FDPsFull-arch FDPs3-4 unit FDPsRates reported (outcome not further specified)
University and private clinic · Regardless of veneering design
Unresolved: the two extractors disagree on this row.
statistically significant difference between 3 and 4-unit FDPs and full-arch restorations (p < 0.001)
GRADE not reported
12 studies
Patients with implant-supported all-ceramic FDPsScrew-retained i-FDPsCement-retained i-FDPsComplications and failure
1 to 5 years follow-up
Incidence rate ratio (IRR) 1.15
GRADE not reported
Studies not reported
Patients with implant-supported all-ceramic 3-4 unit posterior FDPsMonolithic all-ceramic i-FDPsVeneered all-ceramic i-FDPsComplication and failure rate
1 to 5 years follow-up
Unresolved: the two extractors disagree on this row.
Statistically significant difference between monolithic and veneered restorations in complication and failure rate (p < 0.05); no effect size or CI reported
GRADE not reported
Studies not reported
Patients with implant-supported all-ceramic FDPsMicro-veneered all-ceramic i-FDPs (direct comparison)Monolithic all-ceramic i-FDPsSurvival, success, failure and complicationsNone of the included studies directly compared micro-veneered with monolithic i-FDPs
No studies found
0 studies
Patients with anterior implant-supported all-ceramic FDPsMonolithic or micro-veneered all-ceramic i-FDPsVeneered all-ceramic i-FDPsSurvival, success, failure and complicationsNo study reported on anterior i-FDPs
No studies found
0 studies
Patients with implant-supported all-ceramic FDPs spanning 5 to 12 unitsMonolithic or micro-veneered all-ceramic i-FDPsVeneered all-ceramic i-FDPsSurvival, success, failure and complicationsNo study reported on spans between 5 and 12 restored units
No studies found
0 studies

Included primary studies 13

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Carames 2019
Full-arch implant-supported rehabilitations: A prospective study comparing porcelain-veneered zirconia frameworks to monolithic zirconia.
PMID:30521106
2019this review onlynot statednot extracted yet
Cheng 2018
Clinical Results and Technical Complications of Posterior Implant-Supported Modified Monolithic Zirconia Single Crowns and Short-Span…
PMID:29086467
2018this review onlynot statednot extracted yet
Degidi 2018
The Conometric Concept: A 5-Year Follow-up of Fixed Partial Monolithic Zirconia Restorations Supported by Cone-in-Cone Abutments.
PMID:29641625
2018this review onlynot statednot extracted yet
Degidi 2021
Fixed Partial Restorations Made of a New Zirconia-Reinforced Lithium Silicate Material: A 2-Year Short-Term Report.
PMID:33570518
2021this review onlynot statednot extracted yet
Derksen 2021
A Randomized Clinical Trial comparing the clinical fit of CAD/CAM monolithic zirconia Fixed Dental Prostheses (FDP) on ti-base abutments…
PMID:33662051
2021this review onlynot statednot extracted yet
Esquivel-Upshaw 2020
Factors influencing the survival of implant-supported ceramic-ceramic prostheses: A randomized, controlled clinical trial
DOI:10.1016/j.jjodo.2020.100017
2020this review onlynot statednot extracted yet
Esquivel-Upshaw 2020
Factors influencing the survival of implant-supported ceramic-ceramic prostheses: A randomized, controlled clinical trial.
PMID:34059304
2020this review onlynot statednot extracted yet
Ferrini 2018
Digital versus Traditional Workflow for Posterior Maxillary Rehabilitations Supported by One Straight and One Tilted Implant: A 3-Year…
PMID:30534562
2018this review onlynot statednot extracted yet
Koenig 2019
Clinical behavior of second-generation zirconia monolithic posterior restorations: Two-year results of a prospective study with Ex vivo…
PMID:31722238
2019this review onlynot statednot extracted yet
Limmer 2014
Complications and patient-centered outcomes with an implant-supported monolithic zirconia fixed dental prosthesis: 1 year results.
PMID:24393461
2014this review onlynot statednot extracted yet
Papaspyridakos 2013
Computer-assisted design/computer-assisted manufacturing zirconia implant fixed complete prostheses: clinical results and technical…
PMID:22413889
2013this review onlynot statednot extracted yet
Pol 2020
Implant-Supported Three-Unit Fixed Dental Prosthesis Using Coded Healing Abutments and Fabricated Using a Digital Workflow: A 1-Year…
PMID:33284902
2020this review onlynot statednot extracted yet
Spies 2018
Clinical and patient-reported outcomes of zirconia-based implant fixed dental prostheses: Results of a prospective case series 5 years…
PMID:28940708
2018this review onlynot statednot extracted yet

Review question

ElementPlanned (methods)Found (results)
PopulationPartially or completely edentulous patients restored with implant-supported reconstructions with at least one inter-implant ponticPatients with posterior 3-4 unit implant-supported FDPs (9 studies, 330 restorations) and full-arch implant-supported FDPs (3 studies, 210 restorations)
InterventionDental implants restored with monolithic or micro-veneered all-ceramic fixed dental prosthesesMonolithic (233 restorations), micro-veneered (118) and veneered (181) all-ceramic (3Y-TZP zirconia, one zirconia-reinforced lithium disilicate) i-FDPs
ComparisonDental implants restored with veneered all-ceramic fixed dental prosthesesVeneered all-ceramic i-FDPs; only one study directly compared monolithic with veneered i-FDPs
OutcomesSurvival, success, failure and complication rates (biological and technical)Annual failure rate, 3-year survival, annual complication rate, annual chipping rate, 3-year complication-free and chipping-free rates
Study designsRandomized clinical trials and prospective cohort studies (at least 10 participants, follow-up of at least 1 year)2 RCTs and 10 prospective cohort studies (n=12)
TimingMinimum follow-up of 1 yearMean follow-up 2.8 years (3-4 unit) and 2.4 years (full-arch); range 1 to 5 years

AMSTAR 2 items

Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.

ItemExtractor AExtractor BAgree
1Research question includes PICO componentsYesYesyes
2Protocol established before the reviewcriticalPartial YesPartial Yesyes
3Choice of study designs explainedNoNoyes
4Comprehensive literature searchcriticalPartial YesPartial Yesyes
5Study selection in duplicateYesYesyes
6Data extraction in duplicateYesYesyes
7List of excluded studies with reasonscriticalNoNoyes
8Included studies described in detailPartial YesYesno
9Risk of bias assessed satisfactorilycriticalRCT: Yes · NRSI: YesNRSI: Yes · RCT: Yesno
10Funding of included studies reportedNoNoyes
11Appropriate meta-analysis methodscriticalRCT: Yes · NRSI: YesNRSI: Yes · RCT: Yesno
12Impact of risk of bias on the pooled resultsNoNoyes
13Risk of bias accounted for in interpretationcriticalNoNoyes
14Heterogeneity explainedYesYesyes
15Publication bias investigatedcriticalNoNoyes
16Conflicts of interest reportedYesYesyes
OverallCritically LowCritically Lowyes