Non-Cochrane · intervention · PM41910902
Predicting transversal dental arch expansion outcomes with Invisalign aligners in permanent dentition: a systematic review and meta-analysis.
Serafin Marco, Boccalari Elisa, Calò Marta, et al. · Progress in orthodontics · 2026 · PubMed · doi:10.1186/s40510-026-00618-1
Findings
41 findings
| Population | ||||
|---|---|---|---|---|
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion by moderator (univariate random-effects meta-regression) Tooth type (canines vs premolars vs molars) | Meta-regression coefficient (beta, logit scale) 0.031 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Association of hierarchical cluster membership (cusp-level predictability) with covariates Tooth type | Cramer's V 0.19 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Correlation of predictability with planned and achieved expansion Achieved expansion at cusp level | Spearman rho 0.319 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion by moderator (univariate random-effects meta-regression) Achieved expansion (mm) | Meta-regression coefficient (beta, logit scale) 0.534 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, maxillary first molars (16-26) Maxillary first molars 16-26 | Pooled proportion (%) 78 [67, 87] GRADE not reported 26 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion by moderator (univariate random-effects meta-regression) Aligner change interval (7 vs 10 vs 14 days) | Meta-regression coefficient (beta, logit scale) -0.102 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion by moderator (univariate random-effects meta-regression) Publication year | Meta-regression coefficient (beta, logit scale) -0.150 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, mandibular first molars (36-46) Mandibular first molars 36-46 | Pooled proportion (%) 87 [68, 96] GRADE not reported 12 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion by moderator (univariate random-effects meta-regression) Dental arch (maxilla vs mandible) | Meta-regression coefficient (beta, logit scale) 0.393 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion by moderator (univariate random-effects meta-regression) Patient age | Meta-regression coefficient (beta, logit scale) -0.069 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion in the mandibular arch Sensitivity analysis excluding studies at serious risk of bias (mandibular segments) | Sensitivity analyses excluding studies at serious RoB yielded virtually unchanged pooled predictability and heterogeneity estimates (no numbers reported) GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, mandibular second molars (37-47) Mandibular second molars 37-47 | Pooled proportion (%) 73 [12, 98] GRADE not reported 3 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Univariate linear regression of predictability on expansion Achieved expansion | Regression coefficient (beta) 8.75 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Association of hierarchical cluster membership (cusp-level predictability) with covariates Material | Cramer's V 0.20 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Association of hierarchical cluster membership (cusp-level predictability) with covariates Aligner change timing | Cramer's V 0.09 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Independent predictors of predictability (multivariable linear regression) Patient age (per year) | Regression coefficient (beta, % points) -1.102 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, mandibular second premolars (35-45) Mandibular second premolars 35-45 | Pooled proportion (%) 88 [75, 95] GRADE not reported 13 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Independent predictors of predictability (multivariable linear regression) Aligner change timing | p=0.092 (no estimate reported) GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability at gingival margin versus cusp level (difference) Subset of 7 studies reporting both levels, descriptive | Mean difference (percentage points, cusp minus gingival margin) 13.5 GRADE not reported 7 studies |
| Patients in permanent dentition undergoing Invisalign treatment requiring transverse dental arch expansion; maxillary arch | Invisalign clear aligner treatment with digitally planned buccal expansion | Planned (ClinCheck) versus achieved expansion, within-subject | Predictability of expansion in the maxillary arch (SoF) | Range effect 76-83%; 1203 participants (20 non-RCTs); Very low certainty. Very low Downgraded: risk of bias, inconsistency, publication bias 20 studies · 1203 participants |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion by moderator (univariate random-effects meta-regression) Mean planned expansion (mm) | Meta-regression coefficient (beta, logit scale) 0.034 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Association of hierarchical cluster membership (cusp-level predictability) with covariates Age group (<25, 25-35, >35 years) | Cramer's V 0.30 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Association of hierarchical cluster membership (cusp-level predictability) with covariates Arch | Cramer's V 0.16 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, maxillary second molars (17-27) Maxillary second molars 17-27 | Pooled proportion (%) 78 [33, 96] GRADE not reported 5 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, maxillary second premolars (15-25) Maxillary second premolars 15-25 | Pooled proportion (%) 83 [76, 89] GRADE not reported 26 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, maxillary canines (13-23) Maxillary canines 13-23 | Pooled proportion (%) 76 [66, 85] GRADE not reported 25 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Univariate linear regression of predictability on expansion Planned expansion | Regression coefficient (beta) 0.206 GRADE not reported Studies not reported |
| Patients in permanent dentition undergoing Invisalign treatment requiring transverse dental arch expansion; maxillary arch | Invisalign clear aligner treatment with digitally planned buccal expansion | Planned (ClinCheck) versus achieved expansion, within-subject | Predictability of expansion, maxillary arch, sensitivity analysis excluding studies at serious risk of bias Excluding studies at serious risk of bias | Pooled predictability and heterogeneity estimates were very similar to the primary analyses; direction and magnitude unchanged (numbers not reported). GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, maxillary first premolars (14-24) Maxillary first premolars 14-24 | Pooled proportion (%) 81 [73, 87] GRADE not reported 26 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Independent predictors of predictability (multivariable linear regression) Tooth type | p=0.170 (no estimate reported) GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Independent predictors of predictability (multivariable linear regression) Arch (mandibular vs maxillary segments) | Regression coefficient (beta, % points) 13.098 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Correlation of predictability with planned and achieved expansion Planned expansion | Spearman rho -0.058 GRADE not reported Studies not reported |
| Patients in permanent dentition undergoing Invisalign treatment requiring transverse dental arch expansion; maxillary arch | Invisalign clear aligner treatment with digitally planned buccal expansion | Planned (ClinCheck) versus achieved expansion, within-subject | Average predictability of expansion, maxillary arch (all tooth groups) | Average predictability (%) 75.5 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Independent predictors of predictability (multivariable linear regression) Aligner material (LD30 vs EX30) | Regression coefficient (beta, % points) -32.686 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, mandibular canines (33-43) Mandibular canines 33-43 | Pooled proportion (%) 86 [74, 93] GRADE not reported 13 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion, mandibular first premolars (34-44) Mandibular first premolars 34-44 | Pooled proportion (%) 86 [69, 95] GRADE not reported 12 studies |
| Patients in permanent dentition treated with Invisalign aligners requiring transversal dental arch expansion | Invisalign aligners with digitally planned buccal expansion of the maxillary and/or mandibular arch | Planned expansion (within-subject contrast with achieved expansion) | Predictability of expansion by moderator (univariate random-effects meta-regression) Aligner material (LD30 vs EX30) | Meta-regression coefficient (beta, logit scale) -0.530 GRADE not reported Studies not reported |
| Patients in permanent dentition undergoing Invisalign treatment requiring transverse dental arch expansion; mandibular arch | Invisalign clear aligner treatment with digitally planned buccal expansion | Planned (ClinCheck) versus achieved expansion, within-subject | Average predictability of expansion, mandibular arch (all tooth groups) | Average predictability (%) 80.6 GRADE not reported Studies not reported |
| Patients in permanent dentition undergoing Invisalign treatment requiring transverse dental arch expansion; mandibular arch | Invisalign clear aligner treatment with digitally planned buccal expansion | Planned (ClinCheck) versus achieved expansion, within-subject | Predictability of expansion in the mandibular arch (SoF) | Range effect 73-88%; 686 participants (11 non-RCTs); Very low certainty. Very low Downgraded: risk of bias, inconsistency, publication bias 11 studies · 686 participants |
| Patients in permanent dentition treated with Invisalign (maxillary and mandibular tooth groups combined) | Invisalign clear aligner treatment with digitally planned buccal expansion | Planned (ClinCheck) versus achieved expansion, within-subject | Kendall correlation, planned expansion vs predictability | Kendall tau -0.037 GRADE not reported Studies not reported |
| Patients in permanent dentition treated with Invisalign (maxillary and mandibular tooth groups combined) | Invisalign clear aligner treatment with digitally planned buccal expansion | Planned (ClinCheck) versus achieved expansion, within-subject | Kendall correlation, achieved expansion (cusp) vs predictability | Kendall tau 0.218 GRADE not reported Studies not reported |
Included primary studies 40
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Houle 2017 The predictability of transverse changes with Invisalign. PMID:27304231 | 2017 | 1 other review | not stated | not extracted yet |
| Lione 2021 Maxillary arch development with Invisalign system. PMID:33570617 | 2021 | 1 other review | not stated | not extracted yet |
| Tien 2023 The predictability of expansion with Invisalign: A retrospective cohort study. PMID:36195544 | 2023 | 1 other review | not stated | not extracted yet |
| Zhou 2020 Efficiency of upper arch expansion with the Invisalign system. PMID:31368778 | 2020 | 1 other review | not stated | not extracted yet |
| Basudan 2025 Three-dimensional evaluation of the predictability of clear aligners in the treatment of maxillary transverse and anteroposterior tooth… PMID:41159156 | 2025 | this review only | not stated | not extracted yet |
| Bowman 2023 Occlusal contacts and treatment with the Invisalign appliance: a retrospective analysis of predicted vs achieved outcomes DOI:10.2319/102822-738.1 | 2023 | this review only | not stated | not extracted yet |
| Bowman 2023 Occlusal contacts and treatment with the Invisalign appliance: a retrospective analysis of predicted vs achieved outcomes. PMID:36780260 | 2023 | this review only | not stated | not extracted yet |
| Charalampakis 2018 Accuracy of clear aligners: A retrospective study of patients who needed refinement DOI:10.1016/j.ajodo.2017.11.028 | 2018 | this review only | not stated | not extracted yet |
| Charalampakis 2018 Accuracy of clear aligners: A retrospective study of patients who needed refinement. PMID:29957318 | 2018 | this review only | not stated | not extracted yet |
| de-la-Rosa-Gay 2025 Factors affecting expansion predictability of clear aligner treatment. PMID:40257582 | 2025 | this review only | not stated | not extracted yet |
| De-la-Rosa-Gay 2025 Factors affecting expansion predictability of clear aligner treatment DOI:10.1007/s00784-025-06328-y | 2025 | this review only | not stated | not extracted yet |
| Galluccio 2023 Efficacy and Accuracy of Maxillary Arch Expansion with Clear Aligner Treatment DOI:10.3390/ijerph20054634 | 2023 | this review only | not stated | not extracted yet |
| Galluccio 2023 Efficacy and Accuracy of Maxillary Arch Expansion with Clear Aligner Treatment. PMID:36901642 | 2023 | this review only | not stated | not extracted yet |
| Goh 2023 The predictability of the mandibular curve of Wilson, buccolingual crown inclination, and transverse expansion expression with Invisalign… DOI:10.1016/j.ajodo.2021.09.020 | 2023 | this review only | not stated | not extracted yet |
| Goh 2023 The predictability of the mandibular curve of Wilson, buccolingual crown inclination, and transverse expansion expression with Invisalign… PMID:36208968 | 2023 | this review only | not stated | not extracted yet |
| Haouili 2020 Has Invisalign improved? A prospective follow-up study on the efficacy of tooth movement with Invisalign DOI:10.1016/j.ajodo.2019.12.015 | 2020 | this review only | not stated | not extracted yet |
| Haouili 2020 Has Invisalign improved? A prospective follow-up study on the efficacy of tooth movement with Invisalign. PMID:32620479 | 2020 | this review only | not stated | not extracted yet |
| Houle 2017 The predictability of transverse changes with Invisalign DOI:10.2319/122115-875.1 | 2017 | this review only | not stated | not extracted yet |
| Keilig 2024 Treatment Efficiency of Maxillary and Mandibular Orovestibular Tooth Expansion and Compression Movements with the Invisalign® System in… DOI:10.3390/jcm13051267 | 2024 | this review only | not stated | not extracted yet |
| Keilig 2024 Treatment Efficiency of Maxillary and Mandibular Orovestibular Tooth Expansion and Compression Movements with the Invisalign® System in… PMID:38592077 | 2024 | this review only | not stated | not extracted yet |
| Lione 2021 Maxillary arch development with Invisalign system: DOI:10.2319/080520-687.1 | 2021 | this review only | not stated | not extracted yet |
| Medeiros 2024 Accuracy of arch expansion with two thermoplastic materials in Invisalign® patients: EX30® and SmartTrack® DOI:10.1590/2177-6709.29.2.e2423212.oar | 2024 | this review only | not stated | not extracted yet |
| Medeiros 2024 Accuracy of arch expansion with two thermoplastic materials in Invisalign® patients: EX30® and SmartTrack®. PMID:38865514 | 2024 | this review only | not stated | not extracted yet |
| Morales-Burruezo 2020 Arch expansion with the Invisalign system: Efficacy and predictability DOI:10.1371/journal.pone.0242979 | 2020 | this review only | not stated | not extracted yet |
| Morales-Burruezo 2020 Arch expansion with the Invisalign system: Efficacy and predictability. PMID:33301484 | 2020 | this review only | not stated | not extracted yet |
| Nogal-Coloma 2023 Predictability of Maxillary Dentoalveolar Expansion Using Clear Aligners in Different Types of Crossbites DOI:10.3390/app13052963 | 2023 | this review only | not stated | not extracted yet |
| O'Connor 2024 Clinical expression of programmed maxillary buccal expansion and buccolingual crown inclination with Invisalign EX30 and SmartTrack… PMID:38618737 | 2024 | this review only | not stated | not extracted yet |
| Riede 2021 Maxillary expansion or contraction and occlusal contact adjustment: effectiveness of current aligner treatment DOI:10.1007/s00784-021-03780-4 | 2021 | this review only | not stated | not extracted yet |
| Riede 2021 Maxillary expansion or contraction and occlusal contact adjustment: effectiveness of current aligner treatment. PMID:33474622 | 2021 | this review only | not stated | not extracted yet |
| Rocha 2023 Efficiency and Predictability of Coronal Maxillary Expansion Repercussion with the Aligners System: A Retrospective Study DOI:10.3390/dj11110258 | 2023 | this review only | not stated | not extracted yet |
| Rocha 2023 Efficiency and Predictability of Coronal Maxillary Expansion Repercussion with the Aligners System: A Retrospective Study. PMID:37999022 | 2023 | this review only | not stated | not extracted yet |
| Santucci 2023 Assessment of Posterior Dentoalveolar Expansion with Invisalign in Adult Patients DOI:10.3390/ijerph20054318 | 2023 | this review only | not stated | not extracted yet |
| Santucci 2023 Assessment of Posterior Dentoalveolar Expansion with Invisalign in Adult Patients. PMID:36901328 | 2023 | this review only | not stated | not extracted yet |
| Solano-Mendoza 2017 How effective is the Invisalign® system in expansion movement with Ex30′ aligners? DOI:10.1007/s00784-016-1908-y | 2016 | this review only | not stated | not extracted yet |
| Solano-Mendoza 2017 How effective is the Invisalign® system in expansion movement with Ex30' aligners? PMID:27435982 | 2017 | this review only | not stated | not extracted yet |
| Suarez 2025 Comparison of the Predictability of Dentoalveolar Expansion with Different Aligner Systems in Orthodontics: A Longitudinal Clinical Study… DOI:10.3390/app15169074 | 2025 | this review only | not stated | not extracted yet |
| Tien 2023 The predictability of expansion with Invisalign: A retrospective cohort study DOI:10.1016/j.ajodo.2021.07.032 | 2023 | this review only | not stated | not extracted yet |
| Vidal-Bernardez 2021 Efficacy and predictability of maxillary and mandibular expansion with the Invisalign® system. PMID:34306530 | 2021 | this review only | not stated | not extracted yet |
| Vidal-Bernardez 2022 EX30 vs. SmartTrack materials in maxillary expansion with the Invisalign system. PMID:35948311 | 2022 | this review only | not stated | not extracted yet |
| Zhou 2020 Efficiency of Upper Arch Expansion with the Invisalign System DOI:10.2319/022719-151.1 | 2020 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
| Review | Shared studies | Jaccard |
|---|---|---|
| Predictability of maxillary transverse changes with Invisalign in adults: A systematic review and meta-analysis. (2026) | 4 | 0.10 |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Patients in permanent dentition (adolescent or adult) undergoing orthodontic treatment with Invisalign requiring transversal dental arch expansion; mixed or primary dentition, syndromic and surgically assisted expansion excluded | Patients treated with Invisalign for transverse expansion (n=1391 in 23 studies; 21 in meta-analysis); mostly adults |
| Intervention | Invisalign clear aligner therapy with digitally planned buccal expansion of maxillary and/or mandibular arches | Invisalign aligners (LD30/SmartTrack in 12 studies, EX30 in 2, both in 4, unspecified in 5) |
| Comparison | Within-subject contrast between planned and achieved expansion at tooth level | Planned versus achieved expansion |
| Outcomes | Predictability of expansion: ratio of achieved to planned transverse movement (inter-canine, inter-premolar, inter-molar widths or tooth-level cusp/gingival changes) | Pooled predictability by tooth group: maxilla 76-83% (second molars 78%, CI 33-96), mandible 73-88%; average 75.5% maxilla, 80.6% mandible |
| Study designs | RCTs and prospective or retrospective clinical studies (non-RCTs) in vivo | 23 non-randomized studies (20 retrospective, 3 prospective) |
| Timing | Not specified | Not specified |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | Partial Yes | Partial Yes | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | Partial Yes | Partial Yes | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | Yes | Yes | yes |
| 7List of excluded studies with reasonscritical | Yes | Yes | yes |
| 8Included studies described in detail | Partial Yes | Partial Yes | yes |
| 9Risk of bias assessed satisfactorilycritical | NRSI: Yes · RCT: N/A | NRSI: Yes · RCT: N/A | yes |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | NRSI: No · RCT: N/A | NRSI: Yes · RCT: N/A | no |
| 12Impact of risk of bias on the pooled results | Yes | Yes | yes |
| 13Risk of bias accounted for in interpretationcritical | Yes | Yes | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | Yes | Yes | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Low | Moderate | no |