Non-Cochrane · intervention · PM41816658
Efficacy and safety of supraglottic jet oxygenation and ventilation in Chinese patients undergoing bronchoscopic procedures: a systematic review and meta-analysis.
Yang Mingyuan, Li Hong, Cheng Qinghao · Frontiers in medicine · 2026 · PubMed · doi:10.3389/fmed.2026.1721209
Findings
Population Adults (18 years or older) undergoing diagnostic or therapeutic bronchoscopy under procedural sedation, China
33 findings
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Post-procedural sore throat Post-operative · Sensitivity analysis excluding Wu 2017 (fixed effects) | OR 1.71 [1.08, 2.71] GRADE not reported 3 studies · 448 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Jaw lift for hypoxemia Intra-operative | OR 0.09 [0.03, 0.3] Low Downgraded: imprecision, inconsistency 4 studies · 528 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Intraoperative SpO2 (T3) Intra-operative, fixed time points (T3) | MD 2.27 [0.12, 4.42] Low Downgraded: imprecision, inconsistency 8 studies · 745 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Post-procedural nasal bleeding Post-operative | OR 0.7 [0.39, 1.25] Low Downgraded: imprecision, inconsistency 3 studies · 448 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Intraoperative PaCO2 Intra-operative | MD -1.38 [-5.98, 3.22] Low Downgraded: imprecision, inconsistency 7 studies · 605 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | SpO2 at T1 T1 pre-operative | MD -0.17 [-0.67, 0.33] GRADE not reported 9 studies · 805 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Physician satisfaction Procedure | SMD 0.34 [-0.65, 1.32] GRADE not reported 5 studies · 560 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Adjustment of ventilator parameters for hypoxemia Intra-operative | OR 0.05 [0.03, 0.12] Low Downgraded: imprecision, inconsistency 3 studies · 448 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Intraoperative PaO2 Intra-operative, fixed time points | MD 36.31 [6.16, 66.46] Low Downgraded: imprecision, inconsistency 6 studies · 528 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Intraoperative arterial pH Intra-operative | MD -0.04 [-0.12, 0.04] Low Downgraded: imprecision, inconsistency 3 studies · 228 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Heart rate T4 post-operative | MD 1.57 [-1.81, 4.94] GRADE not reported 8 studies · 685 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Intraoperative tachycardia Intra-operative | OR 0.77 [0.13, 4.56] Low Downgraded: imprecision, inconsistency 4 studies · 480 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Jaw lift for hypoxemia Intra-operative · Sensitivity analysis excluding Zha 2021 (fixed effects) | OR 0.06 [0.03, 0.11] GRADE not reported 3 studies · 256 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Incidence of intraoperative hypoxemia Intra-operative | OR 0.2 [0.07, 0.58] Low Downgraded: imprecision, inconsistency 8 studies · 1056 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Heart rate T3 intra-operative | MD 0.92 [-2.57, 4.41] GRADE not reported 8 studies · 685 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Patient satisfaction Procedure | MD 0.06 [-0.58, 0.71] GRADE not reported 5 studies · 560 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | SpO2 at T2 T2 post-induction | MD 1.32 [-0.48, 3.11] GRADE not reported 8 studies · 745 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Intraoperative tachycardia Intra-operative · Sensitivity analysis excluding Wang 2016 (fixed effects) | OR 0.35 [0.14, 0.91] GRADE not reported 3 studies · 452 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Mean arterial pressure T1 pre-operative | MD 0.18 [-0.27, 0.62] GRADE not reported 8 studies · 685 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Mean arterial pressure T4 post-operative | MD -2.13 [-5.52, 1.25] GRADE not reported 8 studies · 685 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Mean arterial pressure T3 intra-operative | MD -4.61 [-10.39, 1.17] GRADE not reported 8 studies · 685 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Total procedure time (minutes) Procedure | MD -2.8 [-5.56, -0.03] GRADE not reported 10 studies · 1013 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Mask ventilation with positive pressure for hypoxemia Intra-operative | OR 0.04 [0.01, 0.12] Low Downgraded: imprecision, inconsistency 4 studies · 528 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | SpO2 at T4 T4 post-operative | MD 1.82 [-0.11, 3.74] GRADE not reported 8 studies · 745 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Intraoperative hypertension Intra-operative | OR 0.2 [0.06, 0.7] Low Downgraded: imprecision, inconsistency 3 studies · 452 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Heart rate T2 post-induction | MD 0.05 [-2.61, 2.72] GRADE not reported 8 studies · 685 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Post-procedural recovery time (minutes) Post-procedural | MD -2.9 [-5.49, -0.3] GRADE not reported 5 studies · 384 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Post-procedural sore throat Post-operative | OR 0.68 [0.15, 3.17] Low Downgraded: imprecision, inconsistency 4 studies · 525 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Post-procedural xerostomia Post-operative | OR 6.08 [2.99, 12.36] Low Downgraded: imprecision, inconsistency 3 studies · 448 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Mean arterial pressure T2 post-induction | MD -6.36 [-14.4, 1.68] GRADE not reported 8 studies · 685 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen therapy (nasal cannula, mask or airway device oxygen; modified laryngeal mask ventilation or Wei Nasal Jet in some trials) | Heart rate T1 pre-operative | MD 1.18 [0.12, 2.24] GRADE not reported 8 studies · 685 participants |
| Supraglottic jet oxygenation and ventilation (SJOV) | Conventional oxygen delivery (nasal cannula, endoscopic face mask) | Incidence of intraoperative hypoxemia Intra-operative · Subgroup by control group: conventional oxygen strategies | OR 0.17 [0.04, 0.65] GRADE not reported Studies not reported |
| Supraglottic jet oxygenation and ventilation (SJOV) | Advanced airway or ventilation strategies (laryngeal mask airway ventilation, Wei Nasal Jet, oral or nasopharyngeal airway) | Incidence of intraoperative hypoxemia Intra-operative · Subgroup by control group: advanced airway or ventilation strategies | OR 0.27 [0.03, 2.16] GRADE not reported Studies not reported |
Included primary studies 8
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Liang 2023a matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Liang 2023b Identification of the different intermediates in the interaction of (A)BC excinuclease with its substrates by DNase I footprinting on two… PMID:2023258 | 1991 | this review only | not stated | not extracted yet |
| Tian 2016 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Wang 2016 [Comparison of the Effectiveness of Different Supraglottic Ventilation Methods during Bronchial Thermoplasty]. PMID:27181886 | 2016 | this review only | not stated | not extracted yet |
| Wei 2024 Supraglottic Jet Oxygenation and Ventilation to Minimize Hypoxia in Patients Receiving Flexible Bronchoscopy Under Deep Sedation: A 3-Arm… PMID:37874765 | 2024 | this review only | not stated | not extracted yet |
| Yang 2021 High frequency jet ventilation through mask contributes to oxygen therapy among patients undergoing bronchoscopic intervention under deep… PMID:33653271 | 2021 | this review only | not stated | not extracted yet |
| Zeng 2023 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Zha 2021 Supraglottic jet oxygenation and ventilation reduces desaturation during bronchoscopy under moderate to deep sedation with propofol and… PMID:33234777 | 2021 | this review only | not stated | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Adults (18 years or older) undergoing diagnostic or therapeutic bronchoscopy with procedural sedation | 1,109 adults undergoing bronchoscopy (555 SJOV, 554 control), ASA I to III, mean age 46 to 73 years, all in China |
| Intervention | Supraglottic jet oxygenation and ventilation (SJOV) | SJOV via Wei Nasal Jet, endoscopic mask, nasopharyngeal or oropharyngeal airway (n=555) |
| Comparison | Conventional oxygen therapy (nasal cannula, mask ventilation) | Nasal cannula, endoscopic mask, nasopharyngeal or oropharyngeal airway oxygen, Wei Nasal Jet, or ventilation via modified laryngeal mask airway (n=554) |
| Outcomes | Incidence of hypoxic events (primary); SpO2, PaO2, PaCO2, need for airway assistance, peri-operative adverse events | Hypoxemia, SpO2, PaO2, jaw lift, ventilator adjustment, mask ventilation, tachycardia, hypertension, pH, PaCO2, sore throat, xerostomia, nasal bleeding, heart rate, MAP, procedure and recovery time, satisfaction |
| Study designs | Randomized controlled trials | 10 RCTs (all China) |
| Timing | Intraoperative and peri-procedural; not specified further | Intraoperative and post-procedural |