Non-Cochrane · prognostic · PM41803535
Epidemiological trends in enamel hypomineralisation and molar-incisor hypomineralisation: a systematic review and meta-analysis.
Ammar Nour, Fresen Karl-Ferdinand, Schwendicke Falk, et al. · Clinical oral investigations · 2026 · PubMed · doi:10.1007/s00784-026-06801-2
Findings
Population Children and adolescents examined in cross-sectional studies of enamel hypomineralisation
14 findings
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) Global | Prevalence 0.155 [0.144, 0.166] GRADE not reported 139 studies · 199999 participants |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) Asia | Prevalence 0.137 [0.119, 0.155] GRADE not reported 44 studies |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) Oceania | Prevalence 0.174 [0.139, 0.208] GRADE not reported 4 studies |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) Africa | Prevalence 0.128 [0.079, 0.177] GRADE not reported 7 studies |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) North America: United States of America | Prevalence 0.109 [0.086, 0.132] GRADE not reported 2 studies |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) North America, original estimate before correction | Prevalence 0.239 [0.144, 0.334] GRADE not reported 6 studies |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) North America: Mexico | Prevalence 0.268 [0.161, 0.374] GRADE not reported 5 studies |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) Europe | Prevalence 0.154 [0.134, 0.174] GRADE not reported 45 studies |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) South America | Prevalence 0.171 [0.151, 0.192] GRADE not reported 29 studies |
| None (prevalence) | None | Prevalence of molar-incisor hypomineralisation (MIH) North America | Prevalence 0.223 [0.140, 0.306] GRADE not reported 7 studies |
| None (prevalence) | None | Prevalence of enamel hypomineralisation (EH) Global | Prevalence 0.253 [0.200, 0.306] GRADE not reported Studies not reported |
| None (prevalence) | None | Prevalence of M + IH (as labeled in Table 1) North America | Prevalence 0.051 [0.033, 0.078] GRADE not reported Studies not reported |
| None (prevalence) | None | Prevalence of M + IH (as labeled in Table 1) North America: United States of America | Prevalence 0.051 [0.033, 0.078] GRADE not reported 2 studies |
| None (prevalence) | None | Prevalence of M + IH (as labeled in Table 1) Global | Prevalence 0.069 [0.060, 0.077] GRADE not reported Studies not reported |
Included primary studies 2
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Tagelsir Ahmed 2020 Prevalence of molar-incisor hypomineralization and other enamel defects and associated sociodemographic determinants in Indiana DOI:10.1016/j.adaj.2020.02.027 | 2020 | this review only | not stated | not extracted yet |
| Tagelsir Ahmed 2020 Prevalence of molar-incisor hypomineralization and other enamel defects and associated sociodemographic determinants in Indiana. PMID:32593351 | 2020 | this review only | Prevalence of molar-incisor hypomineralisation (MIH) | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Not specified | Children examined in epidemiological studies; 199,999 participants in 139 studies; added U.S. cohort of 337 children aged 6 to 15 years |
| Intervention | Not specified | Not applicable (prevalence) |
| Comparison | Not specified | Not applicable (prevalence) |
| Outcomes | Prevalence of molar-incisor hypomineralization and enamel hypomineralization | MIH, EH and M + IH prevalence |
| Study designs | Cross-sectional studies | Cross-sectional studies (n=139) |
| Timing | Not specified | Not specified |