Non-Cochrane · aetiology · PM41692721
Impact of obesity on dental implant failure and peri-implant health: a systematic review and meta-analysis.
Ye Mingfu, Wu Zhang, Lin Xiuwen, et al. · BMC oral health · 2026 · PubMed · doi:10.1186/s12903-026-07908-4
Findings
Population Dental implant patients
12 findings
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Probing depth Follow-up 6 months to over 6 years · Retrospective cohort studies | MD 1.72 [1.18, 2.26] GRADE not reported 3 studies · 302 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Marginal bone loss Follow-up 6 months to over 6 years · Cross-sectional studies | MD 0.84 [0.16, 1.52] GRADE not reported 2 studies · 936 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Implant failure Follow-up 6 months to over 6 years | OR 0.73 [0.29, 1.86] Very low Downgraded: risk of bias, imprecision 4 studies · 17671 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Marginal bone loss Follow-up 6 months to over 6 years | MD 1.20 [0.67, 1.72] Very low Downgraded: risk of bias 5 studies · 1238 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Probing depth Follow-up 6 months to over 6 years | MD 1.56 [1.32, 1.8] Very low Downgraded: risk of bias 5 studies · 1238 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Bleeding on probing Follow-up 6 months to over 6 years · Retrospective cohort studies | SMD 3.60 [2.19, 5.01] GRADE not reported 3 studies · 302 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Marginal bone loss Follow-up 6 months to over 6 years · Retrospective cohort studies | MD 1.44 [0.08, 2.79] GRADE not reported 3 studies · 302 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Plaque index Follow-up 6 months to over 6 years · Retrospective cohort studies | SMD 2.88 [2.22, 3.55] GRADE not reported 2 studies · 209 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Probing depth Follow-up 6 months to over 6 years · Cross-sectional studies | MD 1.08 [0.09, 2.06] GRADE not reported 2 studies · 936 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Bleeding on probing Follow-up 6 months to over 6 years | SMD 2.89 [1.25, 4.53] Very low Downgraded: risk of bias 4 studies · 379 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Implant failure Follow-up 6 months to over 6 years · Retrospective cohort studies | OR 0.73 [0.29, 1.86] GRADE not reported 3 studies · 17551 participants |
| Obesity (BMI >=30 kg/m2, or >=27.5 in two Asian-threshold studies) | Non-obese (BMI below threshold) | Plaque index Follow-up 6 months to over 6 years | SMD 2.24 [0.84, 3.64] Very low Downgraded: risk of bias 3 studies · 286 participants |
Included primary studies 21
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Abduljabbar 2016 Comparison of peri-implant clinical and radiographic inflammatory parameters and whole salivary destructive inflammatory cytokine profile… DOI:10.1016/j.cyto.2016.08.017 | 2016 | this review only | Probing depth; Bleeding on probing; Marginal bone loss | not extracted yet |
| Abduljabbar 2016 Comparison of peri-implant clinical and radiographic inflammatory parameters and whole salivary destructive inflammatory cytokine profile… PMID:27560655 | 2016 | this review only | Probing depth; Bleeding on probing; Marginal bone loss | not extracted yet |
| Alkhudhairy 2018 Comparison of clinical and radiographic peri‐implant parameters among obese and non‐obese patients: A 5‐year study DOI:10.1111/cid.12633 | 2018 | this review only | Plaque index; Probing depth; Bleeding on probing; Marginal bone loss | not extracted yet |
| Alkhudhairy 2018 Comparison of clinical and radiographic peri-implant parameters among obese and non-obese patients: A 5-year study. PMID:30028553 | 2018 | this review only | Plaque index; Probing depth; Bleeding on probing; Marginal bone loss | not extracted yet |
| Elangovan 2014 Body Fat Indices and Biomarkers of Inflammation: A Cross-Sectional Study with Implications for Obesity and Peri-implant Oral Health DOI:10.11607/jomi.3758 | 2014 | this review only | not stated | not extracted yet |
| Elangovan 2014 Body fat indices and biomarkers of inflammation: a cross-sectional study with implications for obesity and peri-implant oral health. PMID:25397806 | 2014 | this review only | not stated | not extracted yet |
| Elsadek 2022 Assessment of clinical and radiographic peri‑implant parameters in the obese and non-obese, along with destructive pro-inflammatory… DOI:10.1016/j.pdpdt.2022.102844 | 2022 | this review only | Plaque index; Probing depth; Bleeding on probing; Marginal bone loss | not extracted yet |
| Elsadek 2022 Assessment of clinical and radiographic peri‑implant parameters in the obese and non-obese, along with destructive pro-inflammatory… PMID:35381370 | 2022 | this review only | Plaque index; Probing depth; Bleeding on probing; Marginal bone loss | not extracted yet |
| Hazem 2016 Comparison of Preprosthetic Implant Complications and Failures Between Obese and Nonobese Patients DOI:10.11607/jomi.4438 | 2016 | this review only | Implant failure | not extracted yet |
| Hazem 2016 Comparison of Preprosthetic Implant Complications and Failures Between Obese and Nonobese Patients. PMID:27632265 | 2016 | this review only | Implant failure | not extracted yet |
| Kayal 2024 Comparison of Peri-Implant Health Parameters among Obese and Non-Obese South Indian Population DOI:10.1615/jlongtermeffmedimplants.2023047398 | 2024 | this review only | Probing depth; Marginal bone loss | not extracted yet |
| Kayal 2024 Comparison of Peri-Implant Health Parameters among Obese and Non-Obese South Indian Population. PMID:38305375 | 2024 | this review only | Probing depth; Marginal bone loss | not extracted yet |
| Knabe 2017 Effect of sex-hormone levels, sex, body mass index and other host factors on human craniofacial bone regeneration with bioactive… DOI:10.1016/j.biomaterials.2017.01.035 | 2017 | this review only | Implant failure | not extracted yet |
| Knabe 2017 Effect of sex-hormone levels, sex, body mass index and other host factors on human craniofacial bone regeneration with bioactive… PMID:28160669 | 2017 | this review only | Implant failure | not extracted yet |
| Mehta 2023 Evaluation of Peri-Implant Parameters and C-Reactive Protein Levels among Patients with Different Obesity Levels. PMID:37694068 | 2023 | this review only | not stated | not extracted yet |
| Oztel 2017 Risk Factors associated with Dental Implant Failure: A Study of 302 Implants placed in a Regional Center DOI:10.5005/jp-journals-10024-2111 | 2017 | this review only | Implant failure | not extracted yet |
| Oztel 2017 Risk Factors associated with Dental Implant Failure: A Study of 302 Implants placed in a Regional Center. PMID:28816194 | 2017 | this review only | Implant failure | not extracted yet |
| Steeds 2025 DOI:10.11607/jomi.10783 | NR | this review only | Implant failure | not extracted yet |
| Steeds 2025 Risk of Dental Implant Failure with Obesity. PMID:39928899 | 2025 | this review only | Implant failure | not extracted yet |
| Vohra 2017 Peri‐implant parameters and C‐reactive protein levels among patients with different obesity levels DOI:10.1111/cid.12556 | 2017 | this review only | Plaque index; Probing depth; Bleeding on probing; Marginal bone loss | not extracted yet |
| Vohra 2017 Peri-implant parameters and C-reactive protein levels among patients with different obesity levels. PMID:29148260 | 2018 | this review only | Plaque index; Probing depth; Bleeding on probing; Marginal bone loss | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Dental implant patients | Dental implant patients; 6838 implants in obese vs 12,071 in non-obese patients in the meta-analysis (n=9 studies) |
| Intervention | Obesity based on BMI (exposure) | Obesity, BMI >=30 kg/m2 (n=9 studies) or >=27.5 kg/m2 Asian WHO cutoff (n=2 studies) |
| Comparison | Non-obese individuals | Non-obese (BMI <30, <25 or 18.5-22.9 depending on study) |
| Outcomes | Implant failure (primary); plaque index, bleeding on probing, probing depth, marginal bone loss (secondary) | Implant failure (n=4); plaque index (n=3); probing depth (n=5); bleeding on probing (n=4); marginal bone loss (n=5) |
| Study designs | No restriction on study design or language | Retrospective cohort (n=7); cross-sectional (n=3); prospective cohort (n=1) |
| Timing | Not specified | Follow-up 6 months to over 6 years |