Non-Cochrane · intervention · PM41664735
Centering Ability and Canal Transportation of Nickel-Titanium (NiTi) Single-File Systems With and Without Glide Path in Extracted Natural Teeth: A Systematic Review and Meta-Analysis.
Manoharan Indumathi, Basu Deblina, Rajan Mathan · Cureus · 2026 · PubMed · doi:10.7759/cureus.101131
Findings
Population Extracted natural posterior teeth (molars) instrumented with single-file NiTi systems
6 findings
| Single-file NiTi instrumentation after glide path preparation | Single-file NiTi instrumentation without glide path preparation | Canal centering ability (centering ratio), apical third Apical third of canal · Laboratory (extracted teeth) | MD 0.08 [0.02, 0.15] GRADE not reported 2 studies · 180 participants |
| Single-file NiTi instrumentation after glide path preparation | Single-file NiTi instrumentation without glide path preparation | Canal centering ability (centering ratio), middle third Middle third of canal · Laboratory (extracted teeth) | MD 0.06 [-0.05, 0.17] GRADE not reported 2 studies · 180 participants |
| Single-file NiTi instrumentation after glide path preparation | Single-file NiTi instrumentation without glide path preparation | Canal transportation, apical third Apical third of canal · Laboratory (extracted teeth) | MD -0.02 [-0.03, -0.01] GRADE not reported 2 studies · 180 participants |
| Single-file NiTi instrumentation after glide path preparation | Single-file NiTi instrumentation without glide path preparation | Canal centering ability (centering ratio), coronal third Coronal third of canal · Laboratory (extracted teeth) | MD 0.011 [0.05, 0.11] GRADE not reported 2 studies · 180 participants |
| Single-file NiTi instrumentation after glide path preparation | Single-file NiTi instrumentation without glide path preparation | Canal transportation, middle third Middle third of canal · Laboratory (extracted teeth) | MD -0.02 [-0.04, -0.01] GRADE not reported 2 studies · 180 participants |
| Single-file NiTi instrumentation after glide path preparation | Single-file NiTi instrumentation without glide path preparation | Canal transportation, coronal third Coronal third of canal · Laboratory (extracted teeth) | MD -0.03 [-0.04, -0.01] GRADE not reported 2 studies · 180 participants |
Included primary studies 3
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Hage 2020 Canal Transportation and Centring Ability of Reciproc and Reciproc Blue With or Without Use of Glide Path Instruments: A CBCT Study. PMID:32766521 | 2020 | this review only | Canal transportation, coronal third; Canal transportation, middle third; Canal transportation, apical third; Canal centering ability (centering ratio), coronal third; Canal centering ability (centering ratio), middle third; Canal centering ability (centering ratio), apical third | not extracted yet |
| Sajad 2018 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Vorster 2018 Canal Transportation and Centering Ability of WaveOne Gold in Combination with and without Different Glide Path Techniques. PMID:30078574 | 2018 | this review only | Canal transportation, coronal third; Canal transportation, middle third; Canal transportation, apical third; Canal centering ability (centering ratio), coronal third; Canal centering ability (centering ratio), middle third; Canal centering ability (centering ratio), apical third | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Extracted natural posterior teeth instrumented with single-file NiTi systems | Extracted maxillary and mandibular molars, curvature 20-40 degrees (n=240 samples; 3 studies) |
| Intervention | Glide path preparation before single-file NiTi instrumentation | Glide path with PathGlider, K-files, Pathfinder or WaveOne Gold Glider files before F6 Sky Taper, WaveOne Gold or Reciproc (n=3) |
| Comparison | No glide path preparation | No glide path preparation (n=3) |
| Outcomes | Centering ability and canal transportation at the apical, middle and coronal thirds | Centering ability (centering ratio) and canal transportation at coronal, middle and apical thirds (2 studies pooled) |
| Study designs | In vitro studies | In vitro studies (n=3) |
| Timing | Not specified | Not specified |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | Partial Yes | Partial Yes | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | No | No | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | No | No | yes |
| 7List of excluded studies with reasonscritical | Yes | Yes | yes |
| 8Included studies described in detail | Partial Yes | Partial Yes | yes |
| 9Risk of bias assessed satisfactorilycritical | RCT: N/A · NRSI: Partial Yes | RCT: N/A · NRSI: Partial Yes | yes |
| 10Funding of included studies reported | Yes | Yes | yes |
| 11Appropriate meta-analysis methodscritical | RCT: N/A · NRSI: No | RCT: N/A · NRSI: No | yes |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | No | No | yes |
| 14Heterogeneity explained | No | No | yes |
| 15Publication bias investigatedcritical | No | No | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Critically Low | Critically Low | yes |