Non-Cochrane · intervention · PM41466863
Radiographic and histomorphometric evaluation of Autogenous Particulated Dentin for Alveolar Ridge Preservation: A Systematic Review and Meta-analyses.
Castells-Mira Enrique, Sánchez-Benito Ferran, Almiñana-Pastor Pedro José, et al. · Journal of clinical and experimental dentistry · 2025 · PubMed · doi:10.4317/jced.63147
Findings
Population Healthy adults (>18 years) requiring extraction of at least one tooth (third molars excluded)
5 findings
| Alveolar ridge preservation with autogenous particulated dentin (APD) | Spontaneous healing (unassisted socket healing) | Vertical ridge height change, lingual bone (CBCT) 4 months of healing | WMD 0.44 [-0.34, 1.22] GRADE not reported 4 studies |
| Alveolar ridge preservation with autogenous particulated dentin (APD) | Spontaneous healing (unassisted socket healing) | Vertical ridge height change, buccal bone (CBCT) 4 months of healing | WMD 0.19 [-1.23, 1.62] GRADE not reported 5 studies |
| Alveolar ridge preservation with autogenous particulated dentin (APD) | Spontaneous healing (unassisted socket healing) | Horizontal ridge width change, coronal third (CBCT) 4 months of healing | WMD 2.04 [0.87, 3.21] GRADE not reported 4 studies |
| Alveolar ridge preservation with autogenous particulated dentin (APD) | Spontaneous healing (unassisted socket healing) | Horizontal ridge width change, middle third (CBCT) 4 months of healing | WMD 1.52 [0.58, 2.45] GRADE not reported 4 studies |
| Alveolar ridge preservation with autogenous particulated dentin (APD) | Spontaneous healing (unassisted socket healing) | Horizontal ridge width change, apical third (CBCT) 4 months of healing | WMD 0.33 [-0.50, 1.16] GRADE not reported 4 studies |
Included primary studies 15
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Elfana 2021 Alveolar ridge preservation using autogenous whole-tooth versus demineralized dentin grafts: A randomized controlled clinical trial. PMID:33565656 | 2021 | 2 other reviews | not stated | not extracted yet |
| Hussain 2023 Efficacy of Autogenous Dentin Biomaterial on Alveolar Ridge Preservation: A Randomized Controlled Clinical Trial. PMID:38179035 | 2023 | 2 other reviews | not stated | not extracted yet |
| Gowda 2024 Autologous tooth bone graft block compared with advanced platelet-rich fibrin in alveolar ridge preservation: A clinico-radiographic study. PMID:38434501 | 2023 | 1 other review | not stated | not extracted yet |
| Santos 2021 Autogenous Mineralized Dentin versus Xenograft granules in Ridge Preservation for Delayed Implantation in Post-extraction Sites: A… PMID:33982320 | 2021 | 1 other review | not stated | not extracted yet |
| Yang 2023 Alveolar ridge preservation in sockets with severe periodontal destruction using autogenous partially demineralized dentin matrix: A… PMID:37455372 | 2023 | 1 other review | not stated | not extracted yet |
| Abo-El-Saad 2023 Autogenous dentin graft versus alloplastic graft combined with socket shield for pre-implant socket preservation: a split-mouth randomized… PMID:36739203 | 2023 | this review only | not stated | not extracted yet |
| Del Canto-Diaz 2019 Use of autologous tooth-derived graft material in the post-extraction dental socket. Pilot study. PMID:30573707 | 2019 | this review only | not stated | not extracted yet |
| Isola 2022 Use of Autogenous Tooth-Derived Mineralized Dentin Matrix in the Alveolar Ridge Preservation Technique: Clinical and Histologic Evaluation. PMID:35830314 | 2022 | this review only | not stated | not extracted yet |
| Joshi 2017 Alveolar ridge preservation using autogenous tooth graft versus beta-tricalcium phosphate alloplast: A randomized, controlled,… PMID:28298826 | 2016 | this review only | not stated | not extracted yet |
| Jung 2018 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Jung 2018 Viral induced cytopathic effect & release of lysosomal enzyme. PMID:220188 | 1978 | this review only | not stated | not extracted yet |
| Minetti 2020 Alveolar Socket Preservation with Different Autologous Graft Materials: Preliminary Results of a Multicenter Pilot Study in Human. PMID:32150927 | 2020 | this review only | not stated | not extracted yet |
| Oguic 2023 Osteogenic Potential of Autologous Dentin Graft Compared with Bovine Xenograft Mixed with Autologous Bone in the Esthetic Zone:… PMID:37047413 | 2023 | this review only | not stated | not extracted yet |
| Sacristan 2024 Use of autologous tooth-derived material as a graft in the post-extraction socket. Split-mouth study with radiological and histological… PMID:39044178 | 2024 | this review only | not stated | not extracted yet |
| Yuceer-Cetiner 2021 Effect of Autogenous Dentin Graft on New Bone Formation. PMID:33405453 | 2021 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Adults over 18 years requiring extraction of at least one tooth (not third molars); healthy patients | 304 participants, 458 sockets (14 articles, 10 randomized trials) |
| Intervention | Alveolar ridge preservation using autogenous particulated dentin (APD) without simultaneous implant placement | APD (14 studies; 5 in meta-analysis) |
| Comparison | Spontaneous healing or other filler material | Spontaneous healing (5 studies in meta-analysis); other graft materials (narrative only) |
| Outcomes | Radiographic horizontal and vertical ridge dimensional changes (minimum 3 months); histomorphometry; complications; need for additional regeneration; PROMs | CBCT horizontal width (coronal, middle, apical third) and vertical height (buccal, lingual) pooled; histomorphometry narrative only |
| Study designs | RCTs and non-randomized clinical trials with parallel arms or split-mouth design | Randomized trials and non-randomized clinical trials; 5 studies in meta-analysis |
| Timing | Minimum healing period of 3 months | Healing 3 to 6 months; meta-analysis at 4 months |