Non-Cochrane · intervention · PM41429866

Clinical performance of short fiber-reinforced composite resin restoration in large posterior cavities: a systematic review and meta-analysis.

Hamdi Kareem, Elsebaai Ahmed, Harp Youniss Saleh, et al. · Scientific reports · 2025 · PubMed · doi:10.1038/s41598-025-31441-z

Findings

Population Participants with vital permanent posterior teeth with large cavities (Class II/MOD or deep) needing restoration

18 findings

Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Adequate marginal adaptation/integrity (USPHS Alpha/Bravo)
12 to 18 months · Sensitivity analysis excluding ElAziz 2020 (indirect nanohybrid comparator)
RR 1.01 [0.92, 1.11]
GRADE not reported
3 studies · 128 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Adequate marginal adaptation/integrity (USPHS Alpha/Bravo)
18 months · Follow-up subgroup: 18 months
RR 1.03 [0.88, 1.21]
GRADE not reported
2 studies · 94 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Adequate color match (USPHS Alpha/Bravo)
12 to 18 months
RR 0.77 [0.57, 1.03]
-230 [-430, 30] per 1,000
Low
Downgraded: imprecision, inconsistency
3 studies · 161 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of post-operative hypersensitivity (USPHS Alpha/Bravo)
12 to 18 months
RR 1.01 [0.96, 1.07]
10 [-39, 68] per 1,000
Low
Downgraded: risk of bias, imprecision
3 studies · 166 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of fracture of restoration (USPHS Alpha/Bravo)
12 to 18 months
RR 1.00 [0.96, 1.04]
0 [-40, 40] per 1,000
Low
Downgraded: risk of bias, imprecision
4 studies · 195 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Adequate marginal adaptation/integrity (USPHS Alpha/Bravo)
12 months · Follow-up subgroup: 12 months
RR 1.25 [1.04, 1.49]
GRADE not reported
2 studies · 101 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of fracture of restoration (USPHS Alpha/Bravo)
18 months · Follow-up subgroup: 18 months
RR 1.00 [0.94, 1.06]
GRADE not reported
2 studies · 94 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of marginal discoloration (USPHS Alpha/Bravo)
12 months · Follow-up subgroup: 12 months
RR 1.07 [0.95, 1.20]
GRADE not reported
2 studies · 101 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of fracture of restoration (USPHS Alpha/Bravo)
12 months · Follow-up subgroup: 12 months
RR 1.00 [0.95, 1.05]
GRADE not reported
2 studies · 101 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of marginal discoloration (USPHS Alpha/Bravo)
18 months · Follow-up subgroup: 18 months
RR 1.00 [0.90, 1.11]
GRADE not reported
2 studies · 94 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Adequate color match (USPHS Alpha/Bravo)
12 to 18 months · Sensitivity analysis excluding ElAziz 2024 (everX Flow)
RR 0.68 [0.55, 0.83]
GRADE not reported
2 studies · 96 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of recurrent (secondary) caries (USPHS Alpha/Bravo)
12 to 18 months
RR 1.00 [0.96, 1.04]
0 [-40, 40] per 1,000
Low
Downgraded: risk of bias, imprecision
4 studies · 195 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of recurrent (secondary) caries (USPHS Alpha/Bravo)
18 months · Follow-up subgroup: 18 months
RR 1.00 [0.94, 1.06]
GRADE not reported
2 studies · 94 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of marginal discoloration (USPHS Alpha/Bravo)
12 to 18 months
RR 1.03 [0.96, 1.12]
27 [-37, 110] per 1,000
Low
Downgraded: risk of bias, imprecision
4 studies · 195 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Adequate surface texture (USPHS Alpha/Bravo)
12 to 18 months
RR 1.00 [0.96, 1.04]
0 [-40, 40] per 1,000
Moderate
Downgraded: imprecision
3 studies · 166 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Absence of recurrent (secondary) caries (USPHS Alpha/Bravo)
12 months · Follow-up subgroup: 12 months
RR 1.00 [0.95, 1.05]
GRADE not reported
2 studies · 101 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Adequate anatomical contact, absence of wear (USPHS Alpha/Bravo)
12 to 18 months
RR 0.99 [0.95, 1.04]
-10 [-50, 40] per 1,000
Low
Downgraded: risk of bias, imprecision
3 studies · 166 participants
Short fiber-reinforced composite (SFRC) restoration (everX Posterior or everX Flow)Conventional resin-based composite (RBC) restoration (nanohybrid or particulate filler)Adequate marginal adaptation/integrity (USPHS Alpha/Bravo)
12 to 18 months
RR 1.10 [0.91, 1.33]
79 [-71, 261] per 1,000
Very low
Downgraded: risk of bias, imprecision, inconsistency
4 studies · 195 participants

Included primary studies 5

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Candan 2013
Clinical performance of fiber-reinforced nanofilled resin composite in extensively carious posterior teeth of children: 30-month evaluation.
PMID:24579274
2013this review onlynot statednot extracted yet
ElAziz 2020
Clinical Performance of Short-fiber-reinforced Resin Composite Restorations vs Resin Composite Onlay Restorations in Complex Cavities of…
PMID:32434978
2020this review onlynot statednot extracted yet
ElAziz 2024
Clinical evaluation of posterior flowable short fiber-reinforced composite restorations without proximal surface coverage.
PMID:38393515
2024this review onlynot statednot extracted yet
Mohamed 2025 (cited as Hamdy et al.)
Clinical performance of class II MOD fiber reinforced resin composite restorations: an 18-month randomized controlled clinical trial.
PMID:39881262
2025this review onlynot statednot extracted yet
Salem 2022
12-months Clinical Evaluation of Fiber Reinforced Bulk Fill Resin Composite versus Incremental Packing of Nanohybrid Resin Composite in…
PMID:36382215
2022this review onlynot statednot extracted yet

Review question

ElementPlanned (methods)Found (results)
PopulationParticipants with vital permanent posterior teeth (molars or premolars) requiring restoration for carious lesions or replacement of defective restorationsParticipants with vital posterior teeth with large cavities, mostly Class II/MOD, ages 8-40 years; 274 patients and 298 restored teeth (n=5 studies; 4 in meta-analysis)
InterventionShort fiber-reinforced composite (SFRC) in large posterior cavities (Class II or MOD involving two or more surfaces, or depth beyond half of dentin thickness)SFRC: ever-X Posterior (3 studies), ever-X Flow (1 study), everStick NET fiber (1 study, not pooled); Ribbond-reinforced arm excluded from pooling
ComparisonConventional direct or indirect resin-based composites (RBCs)Conventional nanohybrid or nanofilled composite, incremental layering or indirect (cemented) composite
OutcomesDurability of the restorations (modified USPHS criteria: hypersensitivity, marginal discoloration, fracture, recurrent caries, color match, marginal adaptation, surface texture, anatomical contact)Eight USPHS clinical parameters pooled as risk ratios (3 to 4 studies each)
Study designsRandomized clinical trials (parallel or split-mouth)RCTs (n=5; 4 parallel arm, 1 mixed split-mouth and parallel)
TimingAt least 12 months follow-up12 to 30 months follow-up (pooled studies 12 and 18 months)