Non-Cochrane · intervention · PM41237595
The Effect of Immediate Dentin Sealing on the Marginal Adaptation and Microleakage of Indirect Restorations: A Systematic Review and Meta-Analysis.
Moghaddas Mohammad Javad, Majidinia Sara, Shahri Arsalan, et al. · International dental journal · 2026 · PubMed · doi:10.1016/j.identj.2025.104017
Findings
Population Prepared human teeth receiving indirect bonded restorations
3 findings
| Immediate dentin sealing (IDS) | Delayed dentin sealing (DDS) | Marginal gap (marginal adaptation) In vitro (laboratory) · All gap studies including Ashy 2020 (gap volume mm3 and gap width um) | SMD 0.28 [-0.77, 0.20] GRADE not reported 3 studies |
| Immediate dentin sealing (IDS) | Delayed dentin sealing (DDS) | Marginal gap (marginal adaptation) In vitro (laboratory) · Sensitivity analysis excluding Ashy 2020 (gap volume mm3) | SMD -0.123 [-0.618, 0.372] GRADE not reported 2 studies |
| Immediate dentin sealing (IDS) | Delayed dentin sealing (DDS) | Microleakage (dye penetration) In vitro (laboratory) | SMD 0.119 [-0.827, 1.065] GRADE not reported 3 studies |
Included primary studies 11
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Ashy 2020 In Vitro Evaluation of Marginal and Internal Adaptations of Ceramic Inlay Restorations Associated with Immediate vs Delayed Dentin Sealing… PMID:31860913 | 2020 | this review only | Marginal gap (marginal adaptation); PM41237595-P1-O3 | not extracted yet |
| de Andrade 2007 Marginal adaptation and microtensile bond strength of composite indirect restorations bonded to dentin treated with adhesive and… PMID:16546249 | 2007 | this review only | Microleakage (dye penetration) | not extracted yet |
| Duarte 2009 The effect of immediate dentin sealing on the marginal adaptation and bond strengths of total-etch and self-etch adhesives. PMID:19573687 | 2009 | this review only | Microleakage (dye penetration) | not extracted yet |
| Elkawash 2024 Influence of Immediate Dentin Sealing on Marginal Gaps of Laminate Veneers: Machinable Monolithic Zirconia Versus Pressable Lithium… PMID:38381991 | 2024 | this review only | Marginal gap (marginal adaptation) | not extracted yet |
| Kanamori 2024 Influence of resin-coating techniques on the marginal adaptation and the bond strengths of CAD/CAM-fabricated hybrid ceramic inlays. PMID:38644215 | 2024 | this review only | not stated | not extracted yet |
| Kitayama 2009 Effect of resin coating on adhesion and microleakage of computer-aided design/computer-aided manufacturing fabricated all-ceramic crowns… PMID:19627359 | 2009 | this review only | Microleakage (dye penetration) | not extracted yet |
| Kitayama 2011 Effect of resin coating and occlusal loading on microleakage of Class II computer-aided design/computer-aided manufacturing fabricated… PMID:21231818 | 2011 | this review only | not stated | not extracted yet |
| Rozan 2020 CAD/CAM-fabricated inlay restorations: Can the resin-coating technique improve bond strength and internal adaptation? PMID:32595190 | 2020 | this review only | not stated | not extracted yet |
| Santana 2016 Effects of Immediate Dentin Sealing and Pulpal Pressure on Resin Cement Bond Strength and Nanoleakage. PMID:26449591 | 2016 | this review only | not stated | not extracted yet |
| Turkistani 2014 Sealing performance of resin cements before and after thermal cycling: evaluation by optical coherence tomography. PMID:24946983 | 2014 | this review only | not stated | not extracted yet |
| Yousif 2023 Effect of immediate dentin sealing on the fracture strength of indirect overlay restorations using different types of luting agents (A… PMID:37705547 | 2023 | this review only | Marginal gap (marginal adaptation) | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Prepared (human) teeth | Extracted human molars, premolars and incisors prepared for indirect restorations (n=11 in vitro studies) |
| Intervention | Bonding with immediate dentin sealing (IDS) | IDS with various adhesives and resin coatings (n=11) |
| Comparison | Bonding with delayed dentin sealing (DDS) | DDS, adhesive applied at cementation (n=11) |
| Outcomes | Marginal integrity (marginal adaptation, e.g. marginal gap) and microleakage (e.g. dye penetration) | Dye penetration microleakage (n=3 studies, 5 comparisons); marginal gap (n=2 studies, 5 comparisons; 3 with Ashy et al) |
| Study designs | In vitro studies on human teeth | In vitro studies (n=11) |
| Timing | Not specified | Not specified |